我国城区门诊支气管哮喘患者疾病严重程度及合并症的调查分析  

Disease severity and comorbidities of outpatients with asthma from urban area in China

作　　者：王文巧[1] 林江涛[1] 刘春涛[2] 周新[3] 王长征 黄茂[5] 蔡绍曦[6] 陈萍[7] 林其昌[8] 周建英[9] 顾玉海[10] 袁雅冬[11] 孙德俊 杨晓红[13] 杨岚[14] 霍建民[15] 陈卓昌[16] 蒋萍[17] 张捷[18] 叶贤伟[19] 刘辉国 唐华平[21] 刘荣玉[22] 张伟[23] 胡成平[24] 陈一强[25] 刘晓菊[26] 戴路明[27] 周玮[28] 黄奕江[29] 许建英 WANG Wenqiao;LIN Jiangtao;LIU Chuntao;ZHOU Xin;WANG Changzheng;HUANG Mao;CAI Shaoxi;CHEN Ping;LIN Qichang;ZHOU Jianying;GU Yuhai;YUAN Yadong;SUN Dejun;YANG Xiaohong;YANG Lan;HUO Jianmin;CHEN Zhuochang;JIANG Ping;ZHANG Jie;YEXianwei;LIU Huiguo;TANG Huaping;LIURongyu;ZHANGWei;HU Chengping;CHEN Yiqiang;LIU Xiaoju;DAI Luming;ZHOU Wei;HUANG Yijiang;XU Jianying(Department of Pulmonary and Critical Care Medicine,China-Japan Friendship Hospital,Beijing 100029,P.R.China;Department of Respiratory Medicine,Qinghai Provincial People's Hospital,Xining,Qinghai 810007,P.R.China;Department of Respiratory Medicine,Second Hospital of Hebei Medical University,Shijiazhuang,Hebei 050000,P.R.China;Department of Respiratory and Critical Care Medicine,Inner Mongolia People's Hospital,Huhhot,Inner Mongolia 010017,P.R.China;Department of Respiratory Medicine,People's Hospital of Xinjiang Uyghur Autonomous Region,Urumqi,Xinjiang 830001,F.R.China;Department of Respiratory and Critical Care Medicine,The First Affiliated Hospital of Xi'an liaotong University,Xi'an,Shaanxi 710061 P.R.China;Department of Respiratory Medicine,First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150001,F.R.China;Department of Respiratory Medicine,Henan Provincial People's Hospita,Zhengzhou,Henan 450003,P.R.China;Department of Respiratory Medicine,Tianjin First Central Hospital,Tianjin 300192,P.R.China;Department of Respiratory and Critical Care Medicine,Second Affiliated Hospital of Jilin University,Changchun,Jilin 130022, P.R.China;Department of Respiratory and Critical Care Medicine,Guizhou Provincial People's Hospital,Guiyang,Guizhou 550002,P.R.China;Department of Respiratory and Critical Care Medicine,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China;Department of Respiratory Medicine,Tongji Hospital of Tongji Medical College,Huazhong University of Science and Technology, Wuhan,Hubei 430030,P.R.China;Department of Respiratory Medicine,Qingdao Municipal Hospital,Qingdao,Shandong 266071,P.R.China;Department of Respira

机构地区：[1]中日友好医院呼吸与危重症医学科,北京100029 [2]四川大学华西医院呼吸与危重症医学科,四川成都610041 [3]上海交通大学医学院第一人民医院呼吸科,上海200080 [4]陆军军医大学新桥医院呼吸内科,重庆410037 [5]江苏省人民医院呼吸与危重症医学科,江苏南京210029 [6]南方医科大学南方医院呼吸与危重症医学科,广东广州510515 [7]沈阳军区总医院呼吸内科,辽宁沈阳110016 [8]福建医科大学附属第一医院呼吸内科,福建福州350005 [9]浙江大学医学院附属第一医院呼吸内科,浙江杭州310003 [10]青海省人民医院呼吸内科,青海西宁810007 [11]河北医科大学第二医院呼吸内科,河北石家庄050000 [12]内蒙古自治区人民医院呼吸与危重症医学科,内蒙古呼和浩特010017 [13]新疆维吾尔自治区人民医院呼吸内科,新疆乌鲁木齐830001 [14]西安交通大学第一附属医院呼吸与危重症医学科,陕西西安710061 [15]哈尔滨医科大学附属第一医院呼吸内科,黑龙江哈尔滨150001 [16]河南省人民医院呼吸内科,河南郑州450003 [17]天津市第一中心医院呼吸科,天津300192 [18]吉林大学第二医院呼吸与危重症医学科,吉林长春130022 [19]贵州省人民医院呼吸与危重症医学科,贵州贵阳550002 [20]华中科技大学同济医学院附属同济医院呼吸内科,湖北武汉430030 [21]青岛市市立医院呼吸科,山东青岛266071 [22]安徽医科大学第一附属医院呼吸内科,安徽合肥230022 [23]南昌大学附属第一医院呼吸科,江西南昌330006 [24]中南大学湘雅医院呼吸内科,湖南长沙410013 [25]广西医科大学第一附属医院呼吸内科,广西南宁530021 [26]兰州大学第一医院呼吸科,甘肃兰州730000 [27]昆明医科大学第一附属医院呼吸内科,云南昆明650032 [28]宁夏医科大学总医院呼吸与危重症医学科,宁夏银川750004 [29]海南省人民医院呼吸内科,海南海口570031 [30]山西大医院呼吸科,山西太

出　　处：《中国呼吸与危重监护杂志》2019年第1期51-56,共6页Chinese Journal of Respiratory and Critical Care Medicine

摘　　要：目的调查我国城区门诊支气管哮喘患者疾病严重程度及合并症。方法 2015年10月至2016年5月于我国内地(除西藏外)30个省、自治区、直辖市的30家三级甲等医院进行面对面问卷调查研究,符合入选标准的门诊哮喘患者纳入研究。研究内容包括:(1)一般资料;(2)吸烟状态;(3)疾病严重程度;(4)合并症。结果本次调查共纳入3 875例门诊哮喘患者。根据GINA指南,疾病严重程度分级:间歇状态52.5%(2 033/3 875),轻度持续24.5%(951/3 875),中度持续16.9%(656/3 875),重度持续6.1%(235/3 875)。体重超重率32.9%(1 274/3 875),肥胖率10.3%(401/3 875);吸烟率为20.1%(777/3 875),其中现行吸烟率为7.7%(298/3 875)。肥胖、吸烟均与哮喘控制不佳相关。75.9%(2 941/3 875)的哮喘患者有合并症,依次为:过敏性鼻炎43.4%(1 682/3 875),高血压病16.4%(634/3 875),鼻窦炎8.7%(338/3 875),慢性阻塞性肺疾病7.3%(283/3 875),支气管扩张症3.0%(118/3 875),鼻息肉2.9%(114/3 875)。结论门诊就诊的哮喘患者轻度占多数。哮喘患者共患过敏性鼻炎、支气管扩张的比例显著高于人群平均水平。肥胖、吸烟均与哮喘控制不佳相关。Objective To investigate the disease severity and comorbidifies in outpatient with asthma from urban area in China.Methods A face-to-face,questionnaire-based survey was carried out in outpatient department in 30 general hospitals from 30 provinces in China mainland except for Tibet during October 2015 to May 2016,and asthma patients who meet the including criteria were enroUed.Data of demographic characteristics,smoking status,disease severity,and comorbidities were collected.Results A total of 3875 cases were included.According to GINA criteria,the proportion of diseases severity was as following:intermittent status 52.5%(2033/3 875),mild persistent 24.5%(951/3 875),moderate persistent 16.9%(656/3 875),and severe persistent 6.1%(235/3 875).The overweight rate was 32.9% (1 274/3 875),the rate of obesity was 10.3%(401/3 875),and the smoking rate was 20.1%(777/3 875).Obesity and smoking were related to poor asthma control.75.9%(2 941/3 875)of the patients had comorbidities:allergic rhinitis 43.4% (1682/3 875),hypertension 16.4%(634/3 875),nasosinusitis 8.7%(338/3 875),chronic obstructive pulmonary disease 7.3% (283/3 875),bronchiectasis 3.0%(118/3 875),and rhinopolypus 2.9%(114/3 875).Conclusions The majority of asthma patients from outpatient department are mild asthma patients.The proportion of allergic rhinitis and bronchiectasis in asthma patients is higher than mean level.Asthma patients with comorbidities of obesity and smoking is related to poor asthma control.

关 键 词：哮喘 横断面研究 问卷调查 合并症 疾病严重程度 

分 类 号：R562.25[医药卫生—呼吸系统]