外源性过敏性肺泡炎的临床治疗进展  

Progress in clinical treatment of extrinsic allergic alveolitis

作　　者：张维[1,2] 罗凤鸣 ZHANG Wei;LUO Fengming(Department of General Medicine,West China Hospital Sichuan University,Chengdu,Sichuan 610041,P.R.China;Department of General Medicine,the People's Hospital of Jianyang City,Jianyang,Sichuan 641500,P.R.China;Department of Respiratory Medicine and Critical Care Medicine,West China Hospital,Sichuan University,Chengdu,Sichuan 610041, P.R.China)

机构地区：[1]四川大学华西医院全科医学科,成都610041 [2]简阳市人民医院全科医学科,四川简阳641500 [3]四川大学华西医院呼吸与危重症医学科,成都610041

出　　处：《华西医学》2019年第1期82-85,共4页West China Medical Journal

摘　　要：外源性过敏性肺泡炎是由于易感人群反复吸入各种具有抗原性的有机粉尘、低分子量化学物质等所引起的Ⅲ型或Ⅳ型变态反应性肺炎的总称,其病变累及肺泡、肺间质和气道,临床上以咳嗽、咳痰和呼吸困难等为主要临床表现。临床上将外源性过敏性肺泡炎分为急性型、亚急性型和慢性型。外源性过敏性肺泡炎会对患者的肺功能造成较大影响,因此早期及时的治疗可以改善患者的临床症状、抑制病情的发展,目前提出的治疗方案主要是避免接触抗原、糖皮质激素治疗、免疫抑制剂治疗、抗纤维化治疗以及肺移植。Extrinsic allergic alveolitis is a general term for type Ⅲ or Ⅳ allergic pneumonia caused by repeated inhalation of various antigenic organic dusts and low molecular weight chemicals in susceptible people. The lesions involve alveolar, pulmonary interstitial, and airway. The main clinical manifestations are cough, expectoration, and dyspnea. Clinically, extrinsic allergic alveolitis is classified into acute, subacute, and chronic forms. Extrinsic allergic alveolitis has a great impact on the pulmonary function of patients. Timely treatment will improve clinical symptoms and inhibit the development of disease. The current treatment plan is mainly avoiding exposure to antigen, glucocorticoid therapy, immunosuppressive therapy, anti-fibrotic therapy, and lung transplantation.

关 键 词：外源性过敏性肺泡炎 临床治疗 进展 

分 类 号：R563.1[医药卫生—呼吸系统]