iQPR法处理水对SD鼠生物安全性的研究  

Study on the Biological Safety of iQPR Treatment Water on SD Mice

作　　者：隋心 贺小英 荆乾鸽 吴宪 郑春丽[1] 张雪峰[1] Sui Xin;He Xiaoying;Jin Qiange;Wu Xian;Zheng Chunli;Zhang Xuefeng(Inner Mongolia University of Science & Technology,Baotou,014000)

机构地区：[1]内蒙古科技大学,包头014000

出　　处：《基因组学与应用生物学》2019年第1期117-122,共6页Genomics and Applied Biology

基　　金：内蒙古自然基金(2017MS(LH)0213)项目资助

摘　　要：iQPR技术处理污水是一项新型尖端的技术,此技术可以成功降低污水乃至受到污染的地下水中的各种污染指标。但是,iQPR技术处理污水尤其是地下水是否存在潜在的生物安全性问题有待于进一步研究。因此,为评估iQPR技术对生物安全性的影响,本研究首先分析了三种不同iQPR法处理水的水质成分;其次系统研究了iQPR水对SD鼠在个体水平、组织水平和病理形态学损伤的研究。研究表明:iQPR处理的水质成分较对照组普通饮用水好,在个体组织水平检测未见异常,尽管其中一组iQPR处理水造成了SD鼠的脾小体增大,但是可能的原因是水处理环节存在微生物污染现象,因此,初步认定此技术未造成SD大鼠的个体损伤。本研究为揭示iQPR处理的水对生物体的安全性评价提供一个理论依据。iQPR technology is a new and advanced technology to treat sewage. This technology can successfully reduce various pollution indicators in sewage and even in the contaminated groundwater.. However, it is necessary to further study the potential biological safety problems of iQPR technology in the treatment of sewage and even contaminated groundwater. Therefore, in order to assess the effects of iQPR on biosafety, firstly this paper analyzed water-quality constituents of three different kinds of water treated by iQPR;Secondly, the effects of iQPR water on the individual level, tissue level and pathological morphology damage of SD mice were studied systematically. The results showed that the water quality components of iQPR treatment were better than the ordinary drinking water in the control group, and no abnormalities at the individual tissue level. Although a group of iQPR treatment water caused the SD rat splenic corpuscle increased, that may be related to microbial bacterial infections drinking water. Therefore it could be initially identified that this technology does not cause individual lesions of SD rats. This study would provide a theoretical basis for revealing the safety of iQPR treatment water to organisms.

关 键 词：iQPR技术 安全评价 水污染 

分 类 号：R99[医药卫生—毒理学] X703[医药卫生—药学]