纤维支气管镜检查联合大剂量氨溴索在免疫损害宿主重症肺炎临床应用的研究  

Study on Clinical Application of Fiberoptic Bronchoscopy Combined with High-Dose Ambroxol in Severe Pneumonia of Immunocompromised Host

作　　者：王海燕[1] 李达宇 WANG Haiyan;LI Dayu(ICU,Huiya Hospital of the First Affiliated Hospital of Sun Yat-sen University,Huizhou 516081,China)

机构地区：[1]中山大学附属第一医院惠亚医院重症医学科,广东惠州516081

出　　处：《临床医学工程》2019年第1期9-10,共2页Clinical Medicine & Engineering

摘　　要：目的研究纤维支气管镜检查联合大剂量氨溴索治疗免疫损害宿主重症肺炎的临床应用效果。方法选择2015年12月至2017年12月我院收治的免疫损害宿主重症肺炎患者53例,随机分为两组。常规组(26例)实施常规治疗及氨溴索治疗,治疗组(27例)在常规治疗基础上加用纤维支气管镜检查联合大剂量氨溴索治疗,对比两组的治疗效果。结果治疗组治疗后的动脉血氧分压、二氧化碳分压、动脉血氧饱和度、呼吸频率、机械通气治疗时间、有效率均优于常规组(P <0.05)。两组的不良反应发生率比较差异无统计学意义(P>0.05)。结论采用纤维支气管镜检查联合大剂量氨溴索治疗免疫损害宿主重症肺炎患者的效果显著,值得临床推广。Objective To study the clinical application effect of fiberoptic bronchoscopy combined with high-dose ambroxol in the treatment of severe pneumonia of immunocompromised host.Methods 53 cases of patients with severe pneumonia of immunocompromised host admitted to our hospital from December 2015 to December 2017 were selected and randomly divided into two groups.The routine group(26 cases)received routine therapy and ambroxol.The treatment group(27 cases)received fiberoptic bronchoscopy combined with high-dose ambroxol.The treatment effects of the two groups were compared.Results The arterial blood oxygen partial pressure,CO2 partial pressure,arterial blood oxygen saturation,respiratory rate,mechanical ventilation treatment time and effective rate after treatment of the treatment group were better than those of the routine group(P<0.05).No statistical difference was found the incidence of adverse reactions between the two groups(P>0.05).Conclusions Fiberoptic bronchoscopy combined with high-dose ambroxol in the treatment of patients with severe pneumonia of immunocompromised host has significant effect,which is worthy of clinical promotion.

关 键 词：纤维支气管镜检查 大剂量氨溴索 免疫损害宿主重症肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]