早期无创机械通气治疗重症肺炎效果的研究  

Reatment outcome of early non-invasive ventilation in patients with severe pneumonia

作　　者：徐海洋[1] 黄晓波[1] XU Haiyang;HUANG Xiaobo(Department of Respiratory,The First People's Hospital of Yinchuan,Yinchuan 750001,China)

机构地区：[1]宁夏银川市第一人民医院呼吸科,宁夏银川750001

出　　处：《宁夏医学杂志》2019年第1期21-23,共3页Ningxia Medical Journal

摘　　要：目的分析早期无创机械通气治疗重症肺炎的效果及预后。方法对85例确诊为重症肺炎患者的临床资料进行回顾性分析。依据是否给予机械通气治疗分为2组:常规治疗组(对照组,n=40)、经面(鼻)无创双水平气道正压通气辅助治疗组(观察组,n=45)。分析患者的一般资料、呼吸困难缓解时间、住院时间、30 d病死率和气压伤发生率,血清D-二聚体、纤维蛋白原、降钙素原等指标在2组中的差异,早期无创机械通气对预后的影响。结果观察组患者呼吸困难缓解时间、住院时间均显著缩短,疗效优于对照组(P<0.05);治疗72 h后观察组患者血清D-二聚体、纤维蛋白原、降钙素原下降较对照组更为明显(P<0.05)。结论早期无创机械通气治疗重症肺炎,可缓解患者的呼吸困难,改善患者的炎症指标和凝血功能,改善患者预后。Objective To explore the clinical effects of early non-invasive mechanical ventilation in patients with severe pneumonia.Methods 85 patients with severe pneumonia were divided into two groups:a conventional treatment group(control group,n=45)and early non-invasive ventilation group(observation group,n=40).The general information including breathing difficulty relief time,length of hospital stay,mortality and incidence of barotrauma 30 days,D-dimer in the serum,fibrinogen,and calcitonin original at the beginning of mechanical ventilation were recorded and compared in the two groups.Results Breathing difficulty relief time,length of hospital stay was lower in observation group(P<0.05);the scale of reducing of D-dimer,fibrinogen,calcitonin original concentration after 72 h treatment in the observation group was higher than control group(P<0.05).Conclusion The severe pneumonia patients will benefit from early non-invasive mechanical ventilation.Clinical symptom,inflammation and blood clotting are improved by early non-invasive mechanical ventilation.

关 键 词：重症肺炎 无创机械通气 治疗效果 

分 类 号：R725[医药卫生—儿科]