降钙素原对于早期诊断经皮肾镜术后尿脓毒血症的临床价值  

Clinical value of procalcitonin in early diagnosis of prostoperative urosepsis after percutaneous nephrolithotomy

作　　者：庄剑秋[1] 陈元贵[1] 褚健[1] 曹建伟[1] 黄钢[1] 章益峰[1] 郎根强[1] Zhnang Jianqiu;Chen Yuangui;Chu Jian;Cao Jianwei;Huang Gang;Zhang Yifeng;Lang Genqiang(Department of Urology,Military 411 Hospital,Shanghai 200081,China)

机构地区：[1]中国人民解放军第411医院泌尿外科,上海200081

出　　处：《国际泌尿系统杂志》2019年第1期94-96,共3页International Journal of Urology and Nephrology

摘　　要：目的通过检测降钙素原(PCT)水平变化,分析降钙素原在早期诊断经皮肾镜碎石术(PCNL)后尿脓毒血症的临床价值。方法回顾性分析本院2015年1月至2016年12月收治的上尿路结石行PCNL的876例患者的临床资料,观察组(PCNL术后继发脓毒血症)56例,对照组820例,统计两组患者术前、术后6hPCT水平并进行比较和统计学分析。结果两组均顺利完成PCNL手术。观察组术前PCT(0.024±0.006)ng/mL,术后6hPCT(5.21±2.22)ng/mL,对照组术前PCT(0.026±0.007)ng/mL,术后6hPCT(1.31±0.29)ng/mL,两组术前PCT水平均在正常范围,两组比较差异无统计学意义(P>0.05);两组术后PCT均有不同程度上升,组内手术前后PCT比较,差异均有统计学意义(P<0.05),两组术后6hPCT组间比较,差异亦有统计学意义(P<0.05)。结论PCNL术后疑是继发脓毒血症时,立即检测血清PCT水平,有助于临床上早期对尿脓毒血症的诊断。Objective By detecting procalcitonin level change, to analysis the clinical value of procalcitonin in early diagnosis of postoperative urosepsis after percutaneous nephrolithotomy(PCNL). Methods Eight hundred and seventy-six patients underwent percutaneous nephrolithotomy of the upper urinary stones were divided into two groups, 56 cases of postoperative urosepsis in observation group (PCNL), 820 cases in control group. Preoperative and postoperative 6 h PCT level of two groups were compared and analyzed. Results Two groups were completed smoothly PCNL. Preoperative PCT of observation group was (0.024±0.006) ng/mL, and postoperative 6 h PCT was (5.21±2.22)ng/mL, preoperative PCT of control group was (0.026±0.007) ng/mL, postoperative 6 h PCT was (1.31±0.29) ng/mL, Preoperative PCT levels of two groups were in normal range, there was no statistically significant difference between the two groups(P>0.05). Comparison of postoperative PCT before and after operation in two group was different degree rise, the differences were statistically significant(P<0.05), after 6 h PCT of two groups was compared, difference was statistically significant(P<0.05). Conclusions PCT levels of patients with suspected secondary sepsis after PCNL are detected , which will help to the early clinical diagnosis of urinary sepsis.

关 键 词：毒血症 降钙素 肾造口术 经皮 

分 类 号：R699[医药卫生—泌尿科学] R459.7[医药卫生—外科学]