桂滇黔交界地区不同胎龄早产儿宫内宫外生长发育迟缓发生状况分析  

Analysis on prevalence of intrauterine and extrauterine growth restriction among premature infants of different gestational age in the border area of Yunnan,Guizhou,and Guangxi

作　　者：梁玉美[1] 杨松媚[1] 延新新 LIANG Yu-Mei;YANG Song-Mei;YAN Xin-Xin(Department of Neonatology,Affiliated Hospital of Youjiang Medical College for Nationalities,Baise,Guangxi 533000, China)

机构地区：[1]右江民族医学院附属医院新生儿科,广西百色533000

出　　处：《中国妇幼保健》2019年第2期321-324,共4页Maternal and Child Health Care of China

基　　金：广西卫生厅自筹经费课题(Z2011136)

摘　　要：目的评价桂滇黔交界地区不同胎龄早产儿出生时宫内生长发育迟缓(IUGR)和出院时宫外生长发育迟缓(EUGR)的发生情况。方法对2014年1月-2015年12月在右江民族医学院附属医院新生儿科住院早产儿的病例资料进行回顾性分析,将入选早产儿按胎龄分3组,即28～31^(+6)周、32～33^(+6)周、34～36^(+6)周,以出生时、出院时体质量小于同胎龄儿生长曲线的第10百分位(<P_(10))定义为IUGR、EUGR,计算其IUGR、EUGR的总发生率,对不同胎龄组出生时IUGR及出院时EUGR的例数及发生率、不同的体质量百分位数出院时与出生时的例数差值及其占该组总例数的比例进行统计,并对其相关性进行分析。结果共674例住院早产儿,出生时IUGR发生率为27. 30%,出院时EUGR发生率为59. 64%,其中出生时IUGR早产儿出院时EUGR发生率达98. 75%。胎龄28～31^(+6)周、32～33^(+6)周、34～36^(+6)周早产儿出生时IUGR发生率分别为6. 67%、25. 37%、35. 41%,组间比较差异有统计学意义(P<0. 05),随着胎龄的增加,IUGR的发生率逐步升高,差异有统计学意义(P<0. 05)。结论桂滇黔交界地区住院早产儿IUGR、EUGR的发生率仍较高,IUGR发生率随着胎龄增大而升高,EUGR发生率随着胎龄、出生体质量百分位数的降低而升高。Objective To evaluate the prevalence of intrauterine growth restriction (IUGR)and extrauterine growth restrietion(EU- GR)among premature infants of different gestational age in the border area of Yunnan,Guizhou,and Guangxi.Methods The medical data of premature infants from Department of Neonatology,Affiliated Hospital of Youjiang Medical College for Nationalities from January 2014 to December 2015 were analyzed retrospectively,all the premature infants were divided into 28-31^+6 week group,32-33^+6 week group,and 34-36^+6 week group.IUGR and EUGR were defined as weight below the 10th percentile for gestational age (<P10 )at birth and when leaving the hospital,respeetively.The total incidence rates of IUGR and EUGR were calculated.The numbers and incidence rates of IUGR at birth and EUGR when leaving the hospital,the differenee value of numbers of premature infants with different percentiles of weight at birth and when leaving the hospital and the proportion of the total number in different gestational age groups were analyzed.The eorrelations were analyzed.Results A total of 674 premature infants were enrolled in this study,the incidence rates of IUGR at birth and EUGR when leaving the hospital were 27.30% and 59.64%,respectively.The incidence rate of EUGR when leaving the hospital in premature infants with IUGR at birth was 98.75%.The incidence rates of IUGR at birth in premature infants during 28-31^+6 weeks,32-33^+6 weeks,and 34-36^+6 weeks were 6.67%,25.37%,and 35.41%,respectively,there were statistically significant differences (P<0.05 ).The incidence rate of IUGR increased gradually with gestational age (P<0.05).Conclusion The incidence rates of IUGR and EUGR are still relatiyely high among hospitalized premature infants in the border area of Yunnan,Guizhou,and Guangxi,the incidence rate of IUGR increases with gestational age,the incidence rate of EUGR increases with decrease of gestational age and percentile of birth weight.

关 键 词：早产儿 不同胎龄 宫内生长发育迟缓 宫外生长发育迟缓 

分 类 号：R714.431[医药卫生—妇产科学]