泄热逐瘀排石汤辅助碎石术对输尿管上段结石的排石效果及肾绞痛的影响  

Clinical study of Xiere-Zhuyu-Paishi decoction and auxiliary lithotripsy for the patients with upper ureteral calculi on the effect of stone removal and renal colic relief

作　　者：徐彦[1] 于波涛 Xu Yan;Yu Botao(Department of Urology,Laiyang Central Hospital of Yantai,Yantai 265200,China)

机构地区：[1]山东省烟台市莱阳中心医院泌尿外科,265200

出　　处：《国际中医中药杂志》2019年第1期27-30,共4页International Journal of Traditional Chinese Medicine

摘　　要：目的观察泄热逐瘀排石汤辅助碎石术对输尿管上段结石患者排石效果及肾绞痛的影响。方法将符合入选标准的80例输尿管上段结石患者按随机数字表法分为2组,每组40例。2组均采用体外冲击波碎石术(extracorporeal shock wave lithotrips, ESWL)碎石,对照组于术后采用西医常规对症治疗,观察组在对照组基础上加服泄热逐瘀排石汤。2组均治疗4周。观察治疗后碎石成功率、结石清除率、结石排出时间及镇痛药物服用情况,以VAS量表评价肾绞痛,以世界卫生组织生存质量测定量表(WHO Quality of Life-BREF, WHOQOL-BREF)评价生活质量,比较临床疗效。结果观察组总有效率为92.5% (37/40)、对照组为75.0%(25/40),2组比较差异有统计学意义(Z=-3.082,P=0.004)。治疗后,观察组结石清除率高于对照组(χ2=3.986,P=0.031),结石排出时间早于对照组(t=6.261,P=0.009),肾绞痛发生率及镇痛药物使用率均低于对照组(χ^2分别为3.146、4.021,P值分别为0.037、0.019),VAS评分低于对照组(t=5.743,P=0.011)。治疗后,观察组WHOQL-BREF总评分及生理领域、心理领域、社会关系领域、环境领域评分均高于对照组(t值分别为6.731、4.342、5.064、4.521、5.128,P值均<0.01)。结论泄热逐瘀排石汤辅助碎石术可提高输尿管上段结石患者的排石效果,缓解肾绞痛,提高生活质量。Objective To observe the effect of stone removal and relieving renal colic with Xiere-Zhuyu-Paishi decoction and auxiliary lithotripsy in patients with upper ureteral calculi.Methods A total of 80 patients with upper ureteral calculi were divided into the observation group and the control group according to the random number table method,with 40 in each group. Both groups were treated with extracorporeal shock wave lithotripsy (ESWL) as the basic treatment. Besides,the control group added the western medicine,such as pain relieving,spasmodic and anti-infection while,the observation group with Xiere-Zhuyu-Paishi decoction. Both groups were treated for 4 weeks. After 1 courses of treatment,the curative effect was evaluated. The effect of lithotripsy (lithotripsy success rate,stone clearance rate,stone expulsion time),renal colic improvement (renal colic rate,analgesic drug usage rate,pain visual analogue VAS score) and WHOQOL-BREF scores were compared.Results After treatment,the total efficiency of observation group was 92.5% (37/40),while the control group was 75% (25/40),and the difference was statistically significant (Z=-3.082,P=0.004). After treatment,the observation group stone clearance rate was 92% (36/40),while the control group was 72.5% (29/40),and the difference was statistically significant (χ^2=3.986,P=0.031). After treatment,the incidence of renal colic of the observation group was 12.5% (5/40),while the control group was 32.5% (13/40),and the difference was statistically significant (χ2=3.146,P=0.037). The analgesic drug usage rate in the observation group was 5% (2/40),while the the control group was 25% (10/40),and the difference was statistically significant (χ^2=4.021,P=0.019). After treatment,the observation group lithecbole time,pain VAS score levels in the observation group was significantly lower than those in the control group (t=6.261,5.743,all Ps<0.01). After treatment,the WHOQL-BREF score,the physiological domain score,psychological field score,social relationship domain score,environ

关 键 词：输尿管结石 碎石术 体外冲击波疗法 排石 肾绞痛 泄热逐瘀排石汤 生活质量 

分 类 号：R699[医药卫生—泌尿科学]