多花山竹子果实化学成分研究  

Chemical constituents from Garcinia multiflora fruits

作　　者：马子玉 卢青秀 年贺凤 腾海达 杨光忠[2,3] 陈玉[1] MA Zi-yu;LU Qing-xiu;Nian He-feng;Teng Hai-da;YANG Guang-zhong;CHEN Yu(College of Chemistry and.Materials Science,South-Central University for Nationalities,Wuhan 430074,China;College of Pharmacy,South-Central University for Nationalities,Wuhan 430074,China;National Demonstration Centerfor Ethnopharmacology Experimental Education,South-Central University for Nationalities, Wuhan 430074,China)

机构地区：[1]中南民族大学化学与材料科学学院,湖北武汉430074 [2]中南民族大学药学院,湖北武汉430074 [3]中南民族大学民族药学国家级实验教学示范中心,湖北武汉430074

出　　处：《中草药》2019年第1期17-21,共5页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(31370379);国家重大新药创制科技重大专项(2017Z09301060);中央高校基本科研业务费资助项目(CZP18004)

摘　　要：目的研究多花山竹子Garciniamultiflora果实化学成分。方法采用正、反相硅胶柱色谱及高效液相色谱等多种技术进行分离纯化,并通过谱学数据鉴定化合物结构。结果从多花山竹子果实乙醇提取物中分离得到了6个化合物,分别鉴定为多花山竹子酮素甲(1)、sargaol(2)、δ-生育三烯酚(3)、木犀草素(4)、1,3,6,7-四羟基酮(5)、对苯二甲酸二(2-乙基)己酯(6)。结论化合物1为新的类金刚烷型间苯三酚类化合物,化合物2、3、6均为首次从该植物中分离得到。Objective To study the chemical constituents of the fruits of Garcinia multiflora. Methods The constituents were isolated and purified by silica gel column chromatography and semipreparative HPLC, and their structures were elucidated by means of spectroscopic analyses. Results Six compounds were obtained and identified as multiflorone A(1), sargaol(2), δ-tocotrienol(3), luteolin(4), 1,3,6,7-tetrahydroxyxanthone(5), terephthalic acid bis(2-ethyl-hexyl) ester(6). Conclusion Compound 1 is a new homoadamantyl type phloroglucinol, and compounds 2, 3 and 6 are isolated from this plant for the first time.

关 键 词：多花山竹子 间苯三酚 多花山竹子酮素甲 δ-生育三烯酚 木犀草素 对苯二甲酸二(2-乙基)己酯 

分 类 号：R284.1[医药卫生—中药学]