一年蓬全草的化学成分研究  

Chemical Constituents of Erigeron annuus Herbs

作　　者：冯卫生[1] 张靖柯 宋楷[1] 李孟[1] 吕锦锦 张志广[1] 郑晓珂[1] FENG Wei-sheng;ZHANG Jing-ke;SONG Kai;LI Meng;LV Jin-jin;ZHANG Zhi-guang;ZHENG Xiao-ke(Henan University of Chinese Medicine,Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province ,Zhengzhou 450046,China)

机构地区：[1]河南中医药大学/呼吸疾病诊疗与新药研发河南省协同创新中心,河南郑州450046

出　　处：《中药材》2018年第4期868-871,共4页Journal of Chinese Medicinal Materials

基　　金：教育部科学技术研究重点资助项目(DF2003078)

摘　　要：目的:研究一年蓬全草的化学成分。方法:利用制备高效液相等各种色谱技术进行化学成分分离,根据理化性质和光谱数据对化合物进行结构鉴定。结果:从一年蓬全草中分离并鉴定16个化合物,分别为:芹菜素-7-O-β-D-(6″-咖啡酰基)吡喃葡萄糖苷(1)、6-甲氧基山柰酚(2)、瑞香素(3)、伞形花内酯(4)、梣皮树脂醇(5)、3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one(6)、3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-one(7)、楝叶吴萸素B(8)、C-藜芦酰乙二醇(9)、L-苯丙氨酸(10)、对羟基苯甲酸(11)、对羟基桂皮酸(12)、丁香酸(13)、对羟基苯乙醇(14)、异黑麦草内酯(15)、异香草酸(16)。结论:所有化合物均为首次从一年蓬中分离得到。Objective:To study the chemical constituents of Erigeron annuus herbs.Methods:The compounds were isolated and identified from ethyl acetate extract by various chromatographic,spectral techniques and the structures were elucidated on the basis of spectral data and physiochemical properties.Results:16 compounds were isolated from Erigeron annuus herbs,and identified as apigenin-7-D-β-D-(6″-caffeoyl)-glucopyranoside(1),6-methoxykaempferol(2),daphnetin(3),umbelliferone(4),medioresinol(5),3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one(6),3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-one(7),evofolin B(8),C-veratryl glycol(9),L-phenylalanine(10),4-hydroxybenzoic acid(11),4-hydroxycinnamic acid(12),syringic acid(13),4-hydroxyphenethyl alcohol(14),epiloliolide(15)and isovanillic acid(16),respectively.Conclusion:All the compounds are isolated from this plant for the first time.

关 键 词：一年蓬 化学成分 苯丙素 酚酸 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]