肝郁脾虚证与肠道菌群相关研究  

Correlation Study Between the Syndrome of Stagnation of Liver Qi and Spleen Deficiency and Intestinal Flora

作　　者：许亚辉[1] 吴佳佳 李杰 薛静 陈家旭 Xu Yahui;Wu Jiajia;Li Jie;Xue Jing;Chen Jiaxu(Basic Medical College,Henan University of Chinese Medicine,Zhengzhou 450046,China;School of Basic Medical Science,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]河南中医药大学基础医学院,郑州450046 [2]北京中医药大学中医学院,北京100029

出　　处：《世界科学技术-中医药现代化》2018年第11期1958-1963,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金委员面上基金项目(81473597):肝郁脾虚型抑郁症海马-杏仁核神经活性甾体变化及逍遥散的作用机理;负责人:陈家旭;国家自然科学基金委重点基金项目(81630104):基于证候病机的逍遥散-肝郁脾虚证方证相关的生物学基础研究;负责人:陈家旭

摘　　要：近年来中医证候学与肠道菌群的关系引起了医学界的广泛关注,肝郁脾虚证作为临床多种疾病常见证候,涉及多系统病变,肠道菌群的紊乱也可引起多系统的病理变化。分子生物学和宏基因组学技术的发展,为证候疾病与肠道菌群的研究提供了有力支持,本文就肝郁脾虚证在神经、消化、内分泌、代谢系统与肠道菌群之间的相关研究作一综述。In recent years, the relationship between TCM(traditional Chinese medicine) syndrome and intestinal flora has attracted wide attention from the medical community. The syndrome of stagnation of liver qi and spleen deficiency is a common clinical syndrome of multiple diseases, involving multiple system pathological change. And the disorganized intestinal flora also cause a multisystem pathological change. The development of molecular biology and metagenomic technology provides strong support for the study of syndrome diseases and intestinal flora. In this paper, it reviewes the correlation of syndrome of stagnation of liver qi and spleen deficiency and intestinal flora in nerve, digestive, endocrine,metabolic system.

关 键 词：肝郁脾虚证 肠道菌群 中医药 

分 类 号：R256.3[医药卫生—中医内科学]