基于国家知识产权局数据库的丹参研究趋势分析  

Research Trend Analysis of Salvia Miltiorrhiza Based on SIOP Database

作　　者：谢志茹 李莎莎[3] 王乐琪 肖雪 李卫东 郭姣 Xie Zhiru;Li Shasha;Wang Leqi;Xiao Xue;Li Weidong;Guo Jiao(Institute of Chinese Medicinal Sciences,Guangdong Pharmaceutical University,Guangzhou 510006,China;Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine,Guangzhou 510006;Guangzhou Province Hospital of Chinese Medicine,Guangzhou 510006,China)

机构地区：[1]广东药科大学中医药研究院,广州510006 [2]广东省代谢病中西医结合研究中心,广州510006 [3]广东省中医院,广州510006

出　　处：《世界科学技术-中医药现代化》2018年第9期1523-1530,共8页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金项目青年基金项目(81603070):基于活性导向和近红外光谱技术的丹参活血化瘀成分转化规律和调配研究;负责人:肖雪;广州市科技计划项目珠江科技新星专项(201610010113):中药生产过程在线近红外光谱检测关键技术研究;负责人:肖雪;广东药科大学"创新强校工程"项目(2015cxqx164):复方贞术调脂胶囊物质基础及过程分析技术的应用研究;负责人:肖雪

摘　　要：丹参为常用大宗中药,具有活血化瘀、通经止痛的功效。丹参药理活性明显,应用广泛,开发潜力巨大。本文通过"中华人民共和国国家知识产权局"专利检索服务系统检索,对已公开丹参专利的申请年度分布及技术衍变趋势、技术生命周期、主要专利权人及专利权人技术分布、技术年度分布、高质量有效专利技术分布等进行统计分析。共检索得到29 468条专利,申请量逐年增长,近几年呈现锐增的趋势,丹参的保健食品类及农业类相关研究近期得到较好的发展;技术生命周期结果显示丹参研究处于成长期;前10位主要专利权人平均专利申请量约为100条,技术格局有所不同;近十年丹参专利技术领域分布出现多样化,主要分布于医药、农业、化工、工程等领域;丹参相关研究的热点领域为A61K35和A61K36,专利质量有待提升。目前丹参研究仍处于快速发展阶段,且涉及范围广泛,在诸多领域有待进一步研究开发。Salvia miltiorrhiza, as one of the top grade herbs in Sheng Nong.s herbal classic, occupies promoting blood circulation function. The pharmacological of Salvia miltiorrhiza is obvious and the relevant research are extensive.However, there is still potential space for development. In this paper, the patents about Salvia miltiorrhiza were analyzed.The patents were collected from Patent Search Service System of"State Intellectual Property Office of the People’s Republic of China". A total of 29 468 patent documents related to Salvia miltiorrhiza were retrieved. The health products and agriculture of Salvia miltiorrhiza has been well developed in recent years. The technology life cycle results show that the research of Salvia miltiorrhiza is in the growth stage. The analyze result shows that the application number were increasing year by year, and the increasing was sharp. The average number of patent applications of the top 10 patent holders is about 100, and the research focus is different. The distribution of patent technology in Salvia miltiorrhiza appears to be diversified, mainly in the fields of medicine, agriculture, chemical engineering and engineering. The results of high-quality and effective patent technology distribution show that classic research fields of Salvia miltiorrhiza are A61 K35 and A61 K36. The research of Salvia miltiorrhiza is still in rapid development stage, and involves a wide range of areas to be further studied and developed.

关 键 词：丹参 专利分析 研究趋势 

分 类 号：R282.71[医药卫生—中药学]