排石汤辅助输尿管镜钬激光碎石术治疗输尿管上段结石临床研究  

Clinical Study of Paishi Tang in Adjuvant Treatment with Ureteroscopic Holmium Laser Lithotripsy for Upper Ureteric Calculi

作　　者：华润淼 邰圣城 於裕福[1] HUA Runmiao;TAI Shengcheng;YU Yufu

机构地区：[1]浙江萧山医院泌尿外科,浙江杭州311200

出　　处：《新中医》2019年第1期119-122,共4页New Chinese Medicine

摘　　要：目的:观察排石汤辅助输尿管镜钬激光碎石术治疗输尿管上段结石的临床效果。方法:选取120例在本院行输尿管镜钬激光碎石术治疗的输尿管上段结石患者120例为研究对象,按随机数字表法分为观察组和对照组,每组60例。2组均采用输尿管镜钬激光碎石术治疗,观察组术后给予排石汤辅助治疗。对比2组术后结石残留率,检测2组手术前后的肾功能指标,统计并发症发生率。结果:术后2天,2组结石残留率比较,差异无统计学意义(P> 0.05)。术后1月及术后3月,观察组结石残留率分别为11.67%和1.67%,低于对照组的26.67%和11.67%,差异均有统计学意义(P <0.05)。术后3月,2组尿素氮(BUN)、血肌酐(SCr)、β2-微球蛋白(β2-MG)水平均较术前降低,差异均有统计学意义(P <0.05);观察组BUN、SCr、β2-MG水平均低于对照组,差异均有统计学意义(P <0.05)。观察组并发症发生率15.00%,对照组并发症发生率8.33%,2组比较,差异无统计学意义(P> 0.05)。结论:排石汤辅助输尿管镜钬激光碎石术治疗输尿管上段结石可获得较好的临床效果,能促进术后残留结石排出,改善患者的肾功能,且并发症发生率较低,值得临床推广应用。Objective:To observe the clinical effect of Paishi tang in adjuvant treatment with ureteroscopic holmium laser lithotripsy for upper ureteral calculi.Methods:Selected 120 cases of patients with upper ureteral calculi treated with ureteroscopic holmium laser lithotripsy in our hospital as study subjects,and divided them into the observation group and the control group by random number table,60 cases in each group.Both groups were treated with ureteroscopic holmium laser lithotripsy,and the observation group was additionally given Paishi tang after operation.Compared the residual stone rates in the two groups,detected the renal function indexes in the two groups before and after operation,and recorded the incidence of complications.Results:There was no significant difference being found in the residual stone rates between the two groups two days after operation(P>0.05).One month and three months after operation,the residual stone rates in the observation group were 11.67%and 1.67%respectively,being lower than those of 26.67%and 11.67%in the control group,differences being significant(P<0.05).Three months after operation,the levels of urea nitrogen(BUN),serum creatinine(SCr)andβ2-microglobulin(β2-MG)in the two groups were lower than those before operation,differences being significant(P<0.05);the BUN,SCr andβ2-MG levels in the observation group were lower than those in the control group,differences being significant(P<0.05).The incidence of complications was 15.00%in the observation group and 8.33%in the control group,compared the two groups,there was no significant difference being found between the two groups(P>0.05).Conclusion:The application of Paishi tang in adjuvant treatment with ureteroscopic holmium laser lithotripsy has good clinical effect in treating upper ureteral calculi with low incidence of complications.It can promote residual stone discharge after operation,and improve renal function of patients,which is worthy of clinical promotion and application.

关 键 词：输尿管上段结石 输尿管镜钬激光碎石术 排石汤 结石残存率 肾功能 并发症 

分 类 号：R693.4[医药卫生—泌尿科学]