消定膏联合七叶皂苷钠治疗桡骨远端骨折对疼痛肿胀及骨代谢指标的影响  

Therapy of Xiaoding Ointment Combined with Aescinate Has Effect on Pain,Swelling and Bone Metabolism Indexes of Distal Radius Fracture

作　　者：魏绍山 WEI Shaoshan

机构地区：[1]商丘市中医院,河南商丘476000

出　　处：《新中医》2019年第1期128-131,共4页New Chinese Medicine

摘　　要：目的:探讨消定膏联合七叶皂苷钠治疗桡骨远端骨折患者的临床效果。方法:将采用切开复位内固定治疗的桡骨远端骨折患者108例分为2组各54例,研究组术后给予消定膏联合七叶皂苷钠及基础治疗,对照组仅给予基础治疗,对比2组患者术后疼痛程度、肿胀程度、骨痂情况及血清相关骨代谢指标的变化。结果:术后第1天,2组的视觉模拟评分法(VAS)评分比较,差异无统计学意义(P> 0.05);术后第3天、术后第7天,研究组VAS评分均低于对照组(P <0.05)。术后第1天,2组肿胀程度评分比较,差异无统计学意义(P> 0.05)。术后第3天、术后第7天,研究组肿胀程度评分均低于对照组(P <0.05)。术后第1天,2组血清碱性磷酸酶(ALP)、骨钙素(BGP)、骨保护素(OPG)、Ⅰ型前胶原羧基端肽(PICP)水平比较,差异无统计学意义(P> 0.05);术后1月,研究组血清ALP、BGP、OPG、PICP水平均高于对照组(P <0.05)。术后第1天,2组的骨痂灰度值水平比较,差异无统计学意义(P> 0.05);术后6周、术后9周,研究组骨痂灰度值均高于对照组(P <0.05)。结论:消定膏联合七叶皂苷钠治疗桡骨远端骨折患者有利于改善患者骨代谢水平、促进骨痂形成、减轻患者术后肿胀及疼痛程度的作用。Objective:To explore the clinical effect of Xiaoding ointment combined with aescinate for distal radius fracture.Methods:Divided 108 cases of patients with distal radius fracture treated with open reduction and internal fixation into two groups randomly,54 cases in each group.The study group received Xiaoding ointment combined with aescinate and basic treatment after operation,while the control group only received basic treatment.Compared the changes in pain degree,swelling degree,callus,serum and bone metabolism indexes after operation in the two groups.Results:On the 1~st day after operation,compared with the scores of visual analogue scale(VAS)in the two groups,there was no significance in thedifference(P>0.05).On the 3~rd and 7~th days after operation,VAS score in the study group was lower than that in the control group(P<0.05).On the 1~st day after operation,compared with the scores of the swelling degree in the two groups,there was no significance in the difference(P>0.05).On the 3~rd and 7~th days after operation,the score of the swelling degree in the study group was lower than that in the control group(P<0.05).On the 1~st day after operation,compared with the levels of alkaline phosphatase(ALP),bone glaprotein(BGP),osteoprotegerin(OPG),carboxyterminal propeptide of type I procollagen(PICP)in serum in the two groups,there was no significance in the difference(P>0.05).On the 1~st month after operation,levels of ALP,BGP,OPG and PICP in serum in the study group were higher than those in the control group(P<0.05).On the1~st day after operation,compared with the value of callus grey in the two groups,there was no significance in the difference(P>0.05).On the 6~th and 9~th weeks after operation,the value of callus grey in the study group was higher than that in the control group(P<0.05).Conclusion:The therapy of Xiaoding ointment combined with aescinate for distal radius fracture can improve the level of bone metabolism,promote the porosis and relieve the swelling and the pain degree of patients after operation

关 键 词：桡骨远端骨折 消定膏 七叶皂苷钠 中医疗法 

分 类 号：R683.41[医药卫生—骨科学]