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作 者:丛晓东[1] 张洁 李灵生 樊茂蓉[1] 张琼[1] CONG Xiaodong;ZHANG Jie;LI Lingsheng;FAN Maorong;ZHANG Qiong
机构地区:[1]中国中医科学院西苑医院,北京100091 [2]北京中医药大学,北京100029
出 处:《新中医》2019年第1期230-232,共3页New Chinese Medicine
基 金:国家中医药管理局国家中医临床研究基地业务建设科研专项(JDZX2015160);中国中医科学院基本科研业务费自主选题(ZZ0908005);国家自然科学基金项目(81673817)
摘 要:以慢性阻塞性肺疾病(COPD)合并肺动脉高压(PH)的现代病理生理为切入点进行分析,追溯"毒瘀"的源流及目前的研究现状,认为毒瘀理论与COPD合并PH有较强的相关性,其中毒邪侵犯机体是导致COPD发病的重要因素;毒邪日久,煎熬津血,发为血瘀,瘀久可再生内毒,两者互为因果,相互交阻,最终导致COPD合并PH;基于其毒瘀相互搏结的特点,解毒祛瘀法是治疗该病的关键方法。Thinking from the perspective of modern pathology and physiology of chronic obstructive pulmonary disease(COPD)complicated with pulmonary hypertension(PH),the authors traced back to the origin and status quo of toxin and blood stasis.It is believed that there exits a relatively strong correlation between COPD complicated with PH and the theory of toxin and blood stasis,among which toxin-evil invading body is an important factor leading to the onset of COPD.Furthermore,toxin-evil retains so long that it will exhaust body fluid and blood to produce blood stasis,which then progressively results in internal toxin if lingering for a long time.As reciprocal causation,they mutually obstruct and stagnate,eventually causing COPD complicated with PH.Based on the feature of Intermingled toxin and blood stasis,the method of eliminating toxin and removing stasis is the key to treating this disease.
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