康复新液联合莫匹罗星软膏治疗腹膜透析隧道口肉芽组织增生的疗效观察  

Effect of Kangfuxin liquid combined with mupirocin on exit-site granulation tissue hyperplasia in peritoneal dialysis patients

作　　者：黄丽秋[1] 徐嘉琪[1] 汤嘉敏[1] 黄汇明 张云芳[1] Huang Liqiu;Xu Jiaqi;Tang Jiamin;Huang Huiming;Zhang Yunfang(Department of Nephrology ,the People's Hospital of Huadu District,Guangzhou ,Guangdong 510800,China;Department of Outpatient,the People's Hospital of Huadu District,Guangzhou ,Guangdong 510800,China)

机构地区：[1]广州市花都区人民医院肾病学科,510800 [2]广州市花都区人民医院门诊部,510800

出　　处：《中国基层医药》2019年第2期154-156,共3页Chinese Journal of Primary Medicine and Pharmacy

基　　金：广东省自然基金(2016A030313420);广东省科技计划项目([2015]110-0024);广东省广州市医学重点学科建设项目(2017-2020);广东省广州市花都区科技计划项目(16-HDWS-015;16-HDWS-30;17-HDWS-001).

摘　　要：目的观察康复新液联合莫匹罗星软膏治疗腹膜透析患者隧道口肉芽组织增生的疗效。方法以2012年1月至2017年12月在广州市花都区人民医院进行腹透治疗并发隧道口肉芽组织增生患者35例为研究对象,采用随机数字表法分为对照组(20例)和治疗组(15例)。对照组采用常规处理;治疗组采用康复新液浸湿的无菌敷料覆盖隧道口。记录治疗前后隧道口肉芽组织转归及并发症发生情况,并进行对比分析。结果对照组痊愈时间为(8.58±1.36)d,治疗组痊愈时间为(3.43±0.85)d,两组差异有统计学意义(t=3.57,P<0.05);对照组有3例并发隧道口渗血,治疗组无并发症。结论康复新液联合莫匹罗星软膏治疗腹膜透析患者隧道口肉芽组织增生疗程短,不良反应少,值得临床推广应用。Objective To observe the effect of Kangfuxin liquid combined with mupirocin on exit-site granulation tissue hyperplasia in peritoneal dialysis patients. Methods From January 2012 to December 2017, 35 peritoneal dialysis patients with exit-site granulation tissue hyperplasia in the People's Hospital of Huadu District were selected and randomly assigned into treatment group (15 cases) and control group(20 cases). The control group was given conventional treatment, the treatment group received a sterile dressing moistened with Kangfuxin liquid.Before and after treatment, the exit-site granulation tissue outcome and the incidence of complications were recorded and compared. Results The recovery time of the control group was (8.58±1.36)d, which was longer than (3.43±0.85)d of the treatment group (t=3.57, P<0.05). Exit-site exudation was found in 3 patients of the control group.No complications were observed in the treatment group. Conclusion Kangfuxin liquid combined with mupirocin can shorter the recovery time of exit-site granulation tissue hyperplasia in peritoneal dialysis patients, and reduce the side effect, which is worthy of clinical application.

关 键 词：腹膜透析 肉芽组织 康复新液 莫匹罗星软膏 

分 类 号：R692.5[医药卫生—泌尿科学]