未足月胎膜早破危险因素分析及对母婴结局的影响  

Risk factors for preterm prelabor rupture of membranes and its impact on maternal and neonatal outcomes

作　　者：高磊[1] 刘晓巍[1] 姜艳[1] 闫震[1] 王建东[1] GAO Lei;JIANG Yah;YAN Zhen;WANG Jian-dong(Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beifing 100026,China)

机构地区：[1]首都医科大学附属北京妇产医院,北京100026

出　　处：《中国临床医生杂志》2019年第2期164-167,共4页Chinese Journal For Clinicians

基　　金：首都卫生发展科研专项基金资助(2016-1-2112)

摘　　要：目的探讨未足月胎膜早破相关危险因素及对母婴结局的影响。方法将未足月胎膜早破患者160例作为观察组,同期收治的足月胎膜早破患者180例作为对照组,回顾性分析两组患者的临床资料,比较其妊娠结局的差异。结果单因素分析及多因素回归分析显示,流产≥2次、生殖道感染为未足月胎膜早破的独立危险因素(P<0. 05)。观察组新生儿感染、新生儿窒息及新生儿呼吸窘迫发生率比对照组高,新生儿体重、新生儿Apgar评分比对照组低,差异有显著性(P<0. 05)。结论临床应对具有多次流产史、生殖道感染等危险因素的高危孕妇加强管理,未足月胎膜早破对新生儿结局有较大不良影响。Objective To investigate the risk factors of preterm prelabor rupture of membranes(PPROM) and its impact on maternal and neonatal outcomes. Method 160 cases of PPROM admitted to our hospital from June 2016 to May 2018 were selected as observation group. 180 cases of full-term PROM during the same period were selected as control group. The clinical data of the two groups were retrospectively analyzed. The pregnancy outcomes of the two groups were recorded,then comparing the two groups of patients with treatment. Result By univariate analysis, abnormal fetal position, abortion( ≥2 times) and reproductive tract infection were the risk factors of PPROM. Multivariate regression analysis showed that abortion( ≥2 times) and reproductive tract infection were independent risk factors for PPROM. The incidence rates of neonatal infection, asphyxia and respiratory distress in the observation group were higher than those in the control group, and the neonatal weight and Apgar score were lower than those in the control group. The difference was statistically significant(P<0. 05). Conclusion Clinical management should be strengthened for high-risk pregnant women with multiple abortion history or reproductive tract infection. PPROM has a great negative effect on neonatal outcome.

关 键 词：未足月胎膜早破 危险因素 母婴结局 

分 类 号：R714[医药卫生—妇产科学]