超声造影联合细针穿刺细胞学检查在80个甲状腺结节定性诊断中的应用价值  

Values of contrast-enhanced ultrasound combined with fine needle aspiration cytology in the qualitative diagnosis of 80 cases of thyroid nodules

作　　者：陈兰[1] 李璐 沈红梅[1] CHEN Lan;LI Lu;SttEN Hongmei(Department of Ultrasonography,Affiliated Hospital of Yanbian University,Yanji 133000,Jilin,China)

机构地区：[1]延边大学附属医院超声科,吉林延吉133000

出　　处：《延边大学医学学报》2018年第3期195-196,共2页Journal of Medical Science Yanbian University

摘　　要：[背景]探讨超声造影(CEUS)联合细针穿刺细胞学(FNA)检查在甲状腺结节定性诊断中的应用价值.[病例报告]选择2016年4月至2017年10月间的二维超声检查较难定性的80个甲状腺结节可疑病灶,同时给行CEUS和FNA检查,对照其结果与术后病理诊断结果.结果见,80个甲状腺结节中良性病变20个(25.0%),恶性病变60个(75.0%).常规二维超声结合CEUS检查诊断敏感度为88.3%(53/60),特异度为70.0%(14/20),准确率为83.8%(67/80);FNA检查诊断敏感度为91.7%(55/60),特异度为65.0%(13/20),准确率为85.0%(68/80);CEUS联合FNA检查诊断敏感度为96.7%(58/60),特异度为75.0%(15/20),准确率为91.3%(73/80);CEUS联合FNA检查与单独CEUS和FNA检查间差异均有统计学意义(P<0.05).[讨论]CEUS联合FNA检查可提高甲状腺病变术前定性诊断的准确率.BACKGROUND To explore the values of contrast-enhanced ultrasound(CEUS)combined with fine needle aspiration cytology(FNA)in the qualitative diagnosis of thyroid nodules.CASE REPORTS 80 suspected thyroid nodules which were difficult to be identified by two-dimensional ultrasound examination between April 2016 and October 2017 were selected.CEUS and FNA examination were performed simultaneously,and their results were compared with the results of postoperative pathological diagnosis.Of the 80 thyroid nodules,20 were benign(25.0%)and 60 were malignant(75.0%).The diagnostic sensitivity of two-dimensional ultrasound combined with CEUS was 88.3%(53/60),the specificity was70.0%(14/20),and the accuracy rate was 83.8%(67/80).The diagnostic sensitivity of FNA was 91.7%(55/60),the specificity was 65.0%(13/20),and the accuracy rate was 85.0%(68/80).The diagnostic sensitivity of CEUS combined with FNA was 96.7%(58/60),the specificity was 75.0%(15/20),and the accuracy rate was 91.3%(73/80).The difference between CEUS combined with FNA and CEUS alone or FNA alone was statistically significant(P<0.05).DISCUSSION The combination of CEUS and FNA could greatly improve the accuracy of preoperative qualitative diagnosis of thyroid lesions.

关 键 词：甲状腺结节 超声造影检查 细针穿刺检查 

分 类 号：R581[医药卫生—内分泌]