基于血管内超声探究冠状动脉病变血管数与最小管腔面积的相关性  

Relationship of the number of stenotic coronary arteries with minimum lumen area from intravascular ultrasound

作　　者：章晓国 王仁云 虞春雷 刘晓恺 汤成春 丁建东 靳激扬[2] ZHANG Xiaoguo;WANG Renyun;YU Chunlei;LIU Xiaokai;TANG Chengchun;DING Jiandong;JIN Jiyang(Department of Cardiology,Zhongda Hospital,Southeast University,Nanfing 210009,China;Department of Imaging,Zhongda Hospital,Southeast University,Nanjing 210009,China)

机构地区：[1]东南大学附属中大医院心血管内科,江苏南京210009 [2]东南大学附属中大医院影像科,江苏南京210009

出　　处：《现代医学》2018年第12期1388-1391,共4页Modern Medical Journal

摘　　要：目的:通过血管内超声(IVUS)测定左前降支近中段病变的最小管腔面积(MLA)及斑块负荷,探究冠心病患者病变血管数量与MLA及斑块负荷的关系。方法:连续、回顾性选取接受冠状动脉造影并同时对左前降支行IVUS检查的冠心病患者91例,男62例,女29例,将其分为单支病变组50例和多支病变组41例,收集其临床资料、病史及实验室检查结果,进行相关性分析。结果:单支病变组与多支病变组之间MLA及斑块负荷差异均有统计学意义(P <0. 001)。冠心病患者病变血管数与MLA呈负相关(r=-0. 413,P <0. 001),病变血管数与斑块负荷呈正相关(r=0. 359,P <0. 001)。结论:冠心病患者病变血管数与MLA及斑块负荷存在相关性。Objective: To explore the association between the number of stenotic coronary arteries and minimum lumen area( MLA) or plaque burden from the intravascular ultrasound( IVUS) of left anterior descending artery.Methods: A total of 91 consecutive patients who underwent both coronary angiography and IVUS of left anterior descending artery were retrospectively enrolled in this study,including 62 males and 29 females. These patients were further divided into single-vessel disease group( 50 cases) and multi-vessel disease group( 41 cases). Their clinical data,medical history and laboratory test results were collected and analyzed by correlation analysis.Results: There were statistically significant differences in MLA and plaque burden between the single-vessel disease group and the multi-vessel disease group( P < 0. 001). The number of stenotic artery in patients with coronary heart disease was negatively correlated with MLA( r =-0. 413,P < 0. 001). The number of stenotic arteries was positively correlated with plaque burden( r = 0. 359,P < 0. 001). Conclusion: There is a correlation between the number of stenotic artery and MLA or plaque burden.

关 键 词：冠心病 血管内超声 最小管腔面积 

分 类 号：R541.4[医药卫生—心血管疾病] R445.1[医药卫生—内科学]