无水乙醇联合博莱霉素在儿童头颈部淋巴管畸形中的介入硬化治疗  

The combination anhydrous ethanol and bleomycin for the interventional treatment of head and neck lymphatic malformations in children

作　　者：潘登 尹传高 汪松 齐炜炜 PAN Deng;YIN Chuangao;WANG Song;QI Weiwei(Imaging Center ,Anhui Children's Hospital,Hefei 230051,China)

机构地区：[1]安徽省儿童医院影像中心,安徽合肥230051

出　　处：《实用放射学杂志》2019年第2期260-262,共3页Journal of Practical Radiology

基　　金：安徽省卫生和计划生育委员会研究基金资助课题(2017ek002).

摘　　要：目的探讨无水乙醇联合博莱霉素在儿童头颈部淋巴管畸形介入硬化治疗中的疗效及优点。方法回顾性分析2016年1月至2018年1月39例儿童头颈部淋巴管畸形的临床资料,治疗前行超声、CT 或 MRI 诊断为淋巴管畸形,并根据检查结果对淋巴管畸形予以分型。根据不同分型选择不同的介入手术方式,在DSA透视或超声引导下,采用无水乙醇联合博莱霉素介入硬化治疗。术后1个月复查,根据疗效决定是否再次治疗。结果39例患儿中38例治疗有效,治疗有效率为97.43%,本组均未出现过敏反应及肺部纤维化等严重不良反应。结论 无水乙醇联合博莱霉素介入硬化治疗儿童头颈部淋巴结畸形的方法安全、有效,且术后并发症少,值得临床推广。Objective To investigate the effect and advantage of the combination anhydrous ethanol and bleomycin for the interventional treatment of head and neck lymphatic malformations in children.Methods The clinical data of 39 children with head and neck lymphatic malformation from January 2016 to January 2018 were reviewed.The type and size of the lymphatic malformations were evaluated by ultrasound,CT or MRI.Different interventionaI procedures were seIected according to their classifications.The interventional sclerotherapy with anhydrous ethanol and bleomycin was injected under the guidance of ultrasound or DSA.Sclerotherapy was repeated when necessary at 1-month follow-up.Results 38 of the 39 cases were effective with the effective rate of 97.43 %.There were no serious adverse reactions such as allergic reaction or pulmonary fibrosis.Conclusion The combination anhydrous ethanol and bleomycin is effective and safe treatment for head and neck lymphatic malformations in children with less complication,and should be used widely.

关 键 词：淋巴管畸形 硬化治疗 无水乙醇 博莱霉素 儿童 

分 类 号：R551.2[医药卫生—血液循环系统疾病] R815[医药卫生—内科学]