血流向量成像技术评价二尖瓣成形患者左心室舒张功能的研究  

Assessment of left ventricular diastolic function by vector flow mapping in patients with mitral valve plasty

作　　者：王莹 李亚南 崔存英 刘园园 胡彦斌 黄丹青 张娟 刘琳 Wang Ying;Li Yanan;Cui Cunying;Liu Yuanyuan;Hu Yanbin;Huang Danqing;Zhang Juan;Liu Lin(Department of Echocardiography,Henan Provincial People's Hospital,Fuwai Central China Cardiovascular Hospital,People's Hospital of Zhengzhou University,Zhengzhou 450003,China)

机构地区：[1]河南省人民医院、阜外华中心血管病医院、郑州大学人民医院超声科,郑州450003

出　　处：《中华超声影像学杂志》2019年第2期93-98,共6页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金(81401419);河南省医学科技攻关计划(201602173,2018020452);河南省科技厅基础与前沿技术研究计划(132300410039).

摘　　要：目的应用血流向量成像(vector flow mapping,VFM)技术评价二尖瓣成形患者手术前后左室舒张功能的变化。方法选取拟行二尖瓣成形术患者30例,应用VFM技术分别于术前1周、术后1周、术后1个月测量左室舒张期不同时相(快速充盈期、缓慢充盈期、心房收缩期)的左室各节段(基底段、中间段、心尖段)及整体的能量损耗,对比分析患者手术前后左室能量损耗的变化。结果与术前1周比较,术后1周左室基底段、中间段在舒张期各时相能量损耗增加,差异有统计学意义(均P<0.05),左室心尖段、整体在舒张期部分时相能量损耗增加,差异有统计学意义(均P<0.05);术后1个月左室各节段及整体在舒张期各时相能量损耗增加,差异有统计学意义(均P<0.05)。与术后1周比较,术后1个月左室各节段及整体的舒张期能量损耗增加,差异有统计学意义(均P<0.05)。结论VFM技术可定量评价二尖瓣成形术患者的左室舒张功能,对手术前后的疗效评估具有临床指导价值。Objective To assess left ventricular diastolic function by vector flow mapping (VFM) in patients with mitral valve plasty. Methods A total of 30 patients undergoing mitral valve plasty were enrolled. The dissipative energy loss (EL) of basal, middle, apical and global left ventricular segments in rapid filing phase, slow filling phase, and atria contract period were measured by VFM, and the EL above were compared in 1 week preoperatively, 1 week and 1 month postoperatively. Results Compared with 1 week preoperatively, EL in all diastole in basal and middle left ventricular segments were significantly increased at 1 week after operation (all P<0.05), EL in some diastole in apical and global left ventricular segments were significantly increased at 1 week after operation (all P<0.05), and EL in all diastole in all left ventricular segments were significantly increased at 1 month after operation (all P<0.05). Compared with 1 week postoperatively, EL in all diastole in all left ventricular segments were significantly increased at 1 month after operation (all P<0.05). Conclusions VFM can quantitatively evaluate left ventricular diastolic function, and helps to evaluate treatment response at preoperative and postoperative.

关 键 词：血流向量成像 二尖瓣成形术 心室功能 左 能量损耗 

分 类 号：R445.1[医药卫生—影像医学与核医学] R654.2[医药卫生—诊断学]