N,N-二(2-吡啶甲基)胺基三聚茚衍生物的合成及对铜离子、镍离子的选择性识别  

N,N-Bis（2-pyridylmethyl）amine-Based Truxene Derivative as a Highly Sensitive Fluorescence Sensor for Cu2+ and Ni2+ Ion

作　　者：朱阳明 王忠龙 杨剑[1] 徐徐[1] 王石发[1] 蔡正春[1] 徐海军[1,2] Zhu Yangmin;Wang Zhonglong;Yang Jian;Xu Xu;Wang Shifa;Cai Zhengchun;Xu Haijun(College of Chemical Engineering, Jiangsu Key Laboratory of Biomass-Based Green Fuels and Chemicals, Nanjing Forestry University, Nanjing 210037;Jiangsu Key Laboratory for Biomass Energy and Material of Jiangsu Province, Nanjing 210042)

机构地区：[1]南京林业大学化学工程学院江苏生物质能源与化学品重点实验室,南京210037 [2]江苏省生物质能源与材料重点实验室,南京210042

出　　处：《有机化学》2019年第2期427-433,共7页Chinese Journal of Organic Chemistry

基　　金：江苏省自然科学基金(No.BK20151513);霍英东教育基金(No.141030);江苏省生物质能源与材料重点实验室(No.JSBGFC12002);江苏高校优势学科建设工程(PAPD)资助项目~~

摘　　要：以二(2-吡啶甲基)胺(DPA)和三聚茚为原料,设计合成了一种"turn-off"型荧光探针化合物6,表征了其结构,研究了它对不同金属离子的识别作用.结果表明,化合物6对Cu^2+和Ni^2+具有较高的灵敏性和选择性,在N,N-二甲基甲酰胺(DMF)/H2O(V/V=8/2,pH=7.0)溶液中对Cu^2+、Ni^2+显示出荧光淬灭效应,且对Cu^2+检测几乎不受其他金属离子的干扰;高分辨质谱证明化合物6与Cu^2+、Ni^2+结合计量比为1:1;化合物6对Cu^2+的检测极限可低至28 nmol/L,对Ni^2+的检测极限可低至41 nmol/L,检测极限均低于世界卫生组织(WHO)规定的饮用水中两种离子最大含量,有潜在的应用价值.A new turn-off probe 6 was synthesized from bis(pyridin-2-ylmethyl)amine and truxene derivatives, and its structure was confirmed by 1H NMR and HRMS. The recognition behaviors of 6 to various metal ions were investigated and the results show that 6 exhibited good selectivity and high sensitivity to Cu^2+ and Ni^2+ with good anti-interference. The probe 6 presented apparent fluorescence quenching in DMF/H2O (V/V=8/2, pH=7.0) solution toward Cu^2+ and Ni^2+. HRMS analysis showed a 1:1 binding stoichiometry between 6 and Cu^2+ or Ni^2+. The detection limit for Cu^2+ and Ni^2+ was calculated to be 28 and 41 nmol/L, respectively. The detection limit of 6 for Cu^2+ and Ni^2+ was far lower than the maximum allowable level of World Health Organization (WHO) limit for drinking water.

关 键 词：三聚茚 二(2-吡啶甲基)胺 荧光探针 CU^2+ NI^2+ 

分 类 号：O657.3[理学—分析化学]