川芎化学成分研究  

Studies on chemical constituents of Ligusticum chuanxiong

作　　者：王文祥[1] 顾明[1] 蒋小岗[1] 顾振纶[1] 范盘生[1] 

机构地区：[1]苏州大学药学系苏州中药研究所,江苏苏州215007

出　　处：《中草药》2002年第1期4-5,共2页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目 ( No.39870 945

摘　　要：目的　研究川芎化学成分。方法　利用硅胶柱层析分离 ,薄层纯化 ,分离川芎化学成分 ,经理化常数测定 ,波谱分析等鉴定结构。结果　共分得 7个化合物 ,分别为正十六烷酸 ( ) ,4,7-二羟基 - 3-丁基苯酞 ( ) ,大黄酚( ) ,咖啡酸 ( ) ,原儿茶酸 ( ) ,阿魏酸 ( )和胡萝卜苷 ( )。结论　化合物 为一新化合物 ,化合物 、 为首次从该植物中分得。Object To study the chemical constituents of Ligusticum chuanxiong Hort.. Methods Some compounds were isolated and purified on silica gel column, their chemical structures were elucidated by their physicochemical properties and spectral data. Results Seven compounds were isolated from the plant and were identified as n-hexadecanoic acid (Ⅰ), 4, 7-dihydroxy-3-butylphthalide (Ⅱ), chrysophanol (Ⅲ), caffeic acid (Ⅳ), protocatechuic acid (Ⅴ), ferulic acid (Ⅵ), daucosterol (Ⅶ) respectively. Conclusion Compounds Ⅰ and Ⅶ were found from this plant for the first time, compound Ⅱ is new.

关 键 词：川芎 结构 4 7-二羟基-3-丁基苯酞 中药 化学成分 

分 类 号：R284.1[医药卫生—中药学]