诊断级超声波辐照对人早孕绒毛组织的影响  

Effects of diagnostic ultrasound on human villi: ultrastructure and hydrogen peroxide cytochemistry observation

作　　者：李卫萍[1] 沙继宏[2] 朱玲仙[3] 叶煦亭[2] 

机构地区：[1]第二军医大学长海医院超声科,上海200433 [2]第二军医大学长海医院基础医学部细胞生物学教研室 [3]长海医院妇产科

出　　处：《第二军医大学学报》2002年第3期314-315,共2页Academic Journal of Second Military Medical University

摘　　要：目的 :研究早孕时经超声辐照后绒毛组织的超微结构变化和细胞化学反应变化。方法 :15例妊娠 6～ 8周健康妇女分为 4组 ,A组 (对照组 ) 3例 ,未行超声辐照 ;B组 4例 ,超声辐照 10 min;C组、D组各 4例 ,辐照 2 0 m in。B、C组超声辐照后即时取材 ,D组超声辐照后 3 d取材。观察绒毛组织超微结构和细胞化学反应的变化。结果 :C组 ,即超声辐照 2 0 m in后即时取材组 ,与正常组相比较绒毛组织有变化 ,合体滋养细胞线粒体嵴间隙及内质网扩张 ,过氧化氢细胞化学反应为阳性 ,合体滋养细胞微绒毛上有致密物沉积。A组、B组、D组均无明显异常。结论Objective:To study the instant and short term effects of diagnostic ultrasound on ultrastructure and hydrogen peroxide cytochemistry of human villi. Methods: Fifteen healthy women with gestational ages of 6 to 8 weeks were divided into 4 groups. Group A( n =3),B( n =4),C( n =4) and D( n =4) were exposured to diagnostic ultrasound for 0,10,20 and 20 min respectively. In group A, B, and C, the villi were taken out immediately after ultrasound exposure and were studied. In group D, the villi were taken out 3 d after ultrasound exposure. Results: The results showed that there were changes only in group C. Enlargement of endoplasmic reticulum and mitochondrial intracristal space were observed in syntrophoblast cells. In group A, B, and D, there were no evident abnormality. Conclusion: The conventional acoustic exposure of diagnostic ultrasound is safe for human villi.

关 键 词：超声检查 绒毛膜绒毛 超微结构 组织细胞化学 早孕 

分 类 号：R714.56[医药卫生—妇产科学] R445.1[医药卫生—临床医学]