吸烟对于抗结核药物性肝损的影响  

The impact of smoking on hypohepatia caused by anti-tuberculosis drugs

作　　者：刘琨[1] 陈洪光[1] 王云南[1] 岑文昌[1] 张丽好[1] 崔柱天[1] 

机构地区：[1]广州市胸科医院,广州510095

出　　处：《广东药学》2002年第2期38-39,共2页Guangdong Pharmaceutical Journal

摘　　要：目的　探讨吸烟对抗结核药物性肝损的影响。方法　对比吸烟者和非吸烟者肺结核患者抗结核治疗中出现的药物性肝损率。结果　吸烟组肝损出现率较对照组升高 ,两者存在显著性差异 (P <0 .0 5)。Objective To study the impact of smoking on hypohepatia caused by anti tuberculosis drugs.Methods The rate of hypohepatia caused by anti tuberculosis was compared between smoking group and non smoking group of pulmonary tuberculosis.Results The rate of hypohepatia in smoking group was remarkably higher than nonsmoking group (P<0.05). Conclusion Smoking may increase the rate of hypohepatia in patients with pulmonary tuberculosis when they are treated by anti tuberculosis drugs.

关 键 词：吸烟 肺结核 肝损伤 抗肺结核药物 

分 类 号：R978.3[医药卫生—药品] R575.1[医药卫生—药学]