骨折愈合塑形的力学机理Ⅱ——骨自优化理论的应用  

MECHANICS IN PLASTIC STAGE OF FRACTURE UNIONⅡ——APPLICATION OF SELF-OPTIMING THEROY OF BONE

作　　者：张春秋[1] 朱兴华[1] 

机构地区：[1]吉林大学力学系,长春130025

出　　处：《中国生物医学工程学报》2002年第2期132-137,共6页Chinese Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目 ( 39970 191) ;吉林省科技发展计划项目 ( 19980 5 5 4 0 1)

摘　　要：采用骨自优化理论与有限元相结合的方法 ,用计算机模拟骨折愈合塑形行为 ,从而定量地分析骨折愈合塑形的力学机理。结果表明 :骨折愈合塑形过程中 ,骨痂的不同类型和骨质疏松的不同层度皆可经过一定时间的塑形以适应受力环境而恢复到骨的正常状态 ;骨在力学环境下调整结构和密度来保持骨的最优结构 ;骨缺损的恢复在缺损处存在恢复到正常状态的密度临界值。本文证实了骨折愈合塑形过程是骨的结构形态对力学环境的最佳适应 ,从而定量的说明了力学环境是引起骨折愈合塑形的主要因素 ,该过程符合Wolff定律。Mechanics in plastic stage of fracture union can be quantitatively analyzed in a computer model by using self-optimizing theroy of bone, integrated with the finite element method. During plastic stage of fracture union, it is found that different sorts of osteotylus and different degrees of osteoporosis are relevant to the recovery of normal state of bone for some time due to adapting itself to the loading conditions to which it is exposed, and that the loading environment can adjust bony structure and density in order to kddp optimal configuration, and the recovery of bony defect needs a critical density at the bony defect. This paper proves the adaption of bone to loading environment during plastic stage of fracture union. The loading environment is the key element to produce remodeling of fracture union during remodeling phase of fracture union, which is in accordance with Wolff′s law.

关 键 词：骨折愈合塑形 自优化理论 有限元 功能适应性 

分 类 号：Q66[生物学—生物物理学] R683[医药卫生—骨科学]