毛细管气相色谱法测定固本咳喘片中补骨脂素和异补骨脂素的含量  

Determination of the psoralen and iospsoralen in Gubenkechuan tablets by CGC method

作　　者：邢旺兴[1] 陈斌[2] 宓鹤鸣[2] 吴玉田[2] 陈士景[1] 

机构地区：[1]解放军第117医院,杭州310013 [2]第二军医大学药学院,上海200433

出　　处：《药学实践杂志》2002年第2期96-97,共2页Journal of Pharmaceutical Practice

摘　　要：目的 :建立超声提取毛细管气相色谱 (CGC)法分离测定中成药固本咳喘片中有效成分补骨脂素和异补骨脂素的含量测定方法。方法 :采用HP - 5毛细管柱 ,氢火焰离子检测器 ,以超声法提取样品 ,用蒽作内标物 ,内标二点法定量。结果 :CGC对补骨脂素和异补骨脂素能达到完全分离。结论OBJECTIVE:To establish capillary gas chromatography(CGC) method for quantitative analysis of the effective components (psoralen and iospsoralen) in Gubenkechuan tablets which extracted by ultrasound method METHODS:The psoralen and iaopsoralen were extracted by ultrasound method, the CGC method is used to separate and determine them using HP-5 capillary column, detected with FID and with two-point method using anthracene as internal standard RESULTS:The psoralen and iospsoralen were separated fully by the CGC method CONCLUSION:The CGC method is a simple and reliable method in the quality control of Gubenkechuan tablets

关 键 词：超声萃取 补骨脂素 异补骨脂素 气相色谱法 

分 类 号：R286.0[医药卫生—中药学]