中国五省农村人群癫痫流行病学抽样调查  

Epidemiological survey on epilepsy among rural populations in five provinces in China

作　　者：王文志[1] 吴建中[1] 王德生[2] 陈桂生[3] 王太平 袁成林[5] 杨斌[6] 赵东海[1] 

机构地区：[1]北京市神经外科研究所,100050 [2]哈尔滨医科大学第一临床医院 [3]宁夏医学院附属医院 [4]山西晋城泽州县医院 [5]扬州医学院附属医院 [6]焦作市人民医院

出　　处：《中华医学杂志》2002年第7期449-452,共4页National Medical Journal of China

基　　金：WHO全球抗癫痫运动示范项目课题资助项目 (20002 0 0 5 )

摘　　要：目的　了解中国农村地区癫痫的患病率以及治疗缺口 ,为开展防治工作提供依据。方法　在黑龙江、宁夏、山西、河南和江苏 5个省 (区 )各选择 1个县作为调查点 ,采用随机整群抽样方法确定调查人群 ,由经过统一培训的医生入户调查。每个点样本要求达 1万人以上 ,5省合计调查 5 56 16人。凡初筛调查时确诊或可疑为癫痫者均经神经科医师再次访查确诊。结果　 5个调查点共确诊癫痫患者 387例 ,患病率为 7 0‰ (标化患病率 6 8‰ )。活动性癫痫患病率为 4 6‰ ,年发病率 2 8 8/10万人口。全部患者中有 4 0 6 %未治疗 ,35 4 %的患者治疗不正规。活动性癫痫的治疗缺口高达6 2 6 %。结论　中国农村地区癫痫患病率大大高于以往报道的数字 ,患者中约有 2 /3以上没有得到正确的治疗 ,应尽快制订合理的干预对策。Objective To investigate the prevalence of epilepsy and its treatment gap in rural areas of China Methods A door to door epidemiological survey on epilepsy was conducted among 55616 rural residents in 5 counties, each in a province (Heilongjiang, Ningxia, Shanxi, Henan, and Jiangsu) selected by random cluster sampling All people diagnosed or suspected as epileptic during the screening phase were rechecked by neurologists Results A definite diagnosis of epilepsy was made among 387 people with a prevalence rate 7 0‰ (age adjusted rate 6 8‰) The prevalence of active epilepsy was 4 6‰, and the incidence of epilepsy was 28 8/100 000 Of the people with epilepsy, 40 6% had not been treated, 35 4% were treated irregularly The treatment gap of active epilepsy was 62 6% Conclusion The prevalence of epilepsy in the rural areas in China was much higher than it was reported previously About two thirds of the patients with epilepsy has not received regular treatment A rational intervention strategy should be developed as soon as possible

关 键 词：癫痫 流行病学 患病率 抽样调查 农村 中国 

分 类 号：R195.1[医药卫生—卫生统计学]