母亲丙型肝炎病毒血清学标志与子代受染的关系  

THE RELATIONSHIP BETWEEN MOTHER'S HCV SERUM MARKS AND INFECTION OF FETUS.

作　　者：王珊珊[1] 刘淑文[2] 李珉珉 彭桂福[1] 曾年华[1] 王志斌[1] 李兴国[1] 唐忠云 

机构地区：[1]广州军区军事医学研究所 [2]第一军医大学 [3]广州华侨医院 [4]54438部队

出　　处：《现代预防医学》2002年第2期135-136,共2页Modern Preventive Medicine

基　　金：广东省科委资助课题 ( 970 0 2 )

摘　　要：目的 :探讨母亲丙型肝炎病毒血清学标志与子代受染之间的关系。方法 :选择母亲与胎儿抗 - HCV均阳性者为研究对象 ,检测母亲与胎儿的抗 - HCV、HCV RNA、抗 - HCV的型别。结果 :16对母亲与胎儿抗 - HCV均阳性 ,血清分型一致。其中 12例母亲 HCV RNA阳性 ,其胎儿 6例阳性。 4例阴性母亲的胎儿 HCV RNA均阴性。结论 :母亲 HCV RNA阳性其子代受染率为 5 0 %Objective:A study was carried out to observe the relationship between mother's HCV serum marks and infection of fetus.Methods:Anti-HCV,HCV RNA,serotype of mothers and fetus were detected.Results:The serum anti-HCV of 16 pairs of mother and fetus were positive.The serotype of mothers and fetus were consistent.HCV RNA of 12 mothers and 6 fetus were positive,4 fetus born to the 4 HCV DNA negative mothers were all negative.Conclusion:The HCV infection rate of the fetus born to mother for HCV RNA was 50%.

关 键 词：丙型肝炎病毒 宫内传播 子代受染 血清学标志 

分 类 号：R512.63[医药卫生—内科学] R373.21[医药卫生—临床医学]