18-氨基酸注射液在全合一营养液中稳定性的研究  

Study on the stability of 18-amino acids injection in all-in-one nutrient admixture

作　　者：黎卫明 李帼蓉 廖颂明 

机构地区：[1]广州侨光制药厂,广东广州510140

出　　处：《广东药学院学报》2002年第1期38-40,共3页Academic Journal of Guangdong College of Pharmacy

摘　　要：目的 :研究国产 18-氨基酸注射液 ( 12 % )在国产注射剂组成的全合一营养液中的稳定性。方法 :用 18-氨基酸注射液( 12 % )与脂肪乳剂、葡萄糖、维生素、微量元素、电解质等营养注射剂混合在单一容器——— 3L输液袋中 ,在室温 2 5℃放置 1d ,移至4℃保存 8d后再于 2 5℃放置 1d ,在此期间分别在 0、1、10d抽样。用氨基酸分析仪测定各种氨基酸的含量 ,以第 0d分别与第 1d、第 10d比较 ,观察各种氨基酸的稳定性。结果与结论 :观察期内该研究的 18-氨基酸注射液在全合一营养液中是稳定的。Objective: To study the stability of the domestic 18 amino acids injection (12% ) in all in one nutrient admixture. Method: 18 amino acids injection (12%),fat emulsion,glucose,vitamins,trace elements and electrolytes were mixed in a 3 L infusion bag and stored at 25 ℃ for 1 day,followed by 4 ℃ for 8 days and 25 ℃ for 1 day. The content of the amino acids were determined through an amino acids analyzer on days 0,1 and 10 to evaluate the stability of the amino acids. Result and Conclusion: No significant changes of the content of the 18 amino acids injection (12% )occurred during the study period.

关 键 词：氨基酸注射液 全合一营养液 稳定性 

分 类 号：R944[医药卫生—药剂学]