三相相转移催化合成对硝基苯甲醚的研究  

Study on synthesis of p-nitroanisole by using tri- phase transfer catalyst

作　　者：章亚东[1] 高晓蕾[1] 蒋登高[1] 王自健[1] 

机构地区：[1]郑州大学化工学院,郑州450002

出　　处：《现代化工》2002年第1期27-30,共4页Modern Chemical Industry

摘　　要：合成制备了聚苯乙烯支载聚乙二醇 ,并以之作为三相相转移催化剂用于对硝基氯苯合成对硝基苯甲醚 ,考察了催化剂、NaOH、CH3OH等的用量对反应转化率的影响 ,得到了适宜的合成工艺条件为 :n(PCNB)∶n(CH3OH)∶n(NaOH)∶n(PTC) =1∶3∶3∶(0 0 3～ 0 0 5) ,反应温度约 78～ 80℃ ,反应时间 9～ 1 0h。在该条件下 ,对硝基氯苯转化率大于 99 5 % ,收率大于 95 % ,产品经气相色谱检测纯度达 99 7% ,聚苯乙烯支载聚乙二醇催化剂可重复使用 5次以上 ,反应母液经除盐后 。Polystyrene supported polyethylene glycol was synthesized and used as tri phase phase transfer catalyst (TPPTC) in the synthesis of p nitroanisole from p chloronitrobenzene.Effects of catalyst,NaOH,and CH 3OH on the reaction conversion rate were studied and optimal synthesizing conditions derived were as follows: n (PCNB)∶ n (CH 3OH)∶ n (NaOH)∶ n (PTC)=1∶3∶3∶(0 03-0 05),temperature 78-80℃ and reaction time 9-10 h.Under such conditions the conversion rate of p chloronitrobenzene can be higher than 99 5% with the yield better than 95% and the product purity measured by gas chromatography can reach 99 7%.The catalyst can be used five times or even more.Water phase solution after desalting and adding base can be reused with no negative effect on the reaction.

关 键 词：聚苯乙烯 反应转化率 催化剂 聚乙二醇 

分 类 号：TQ246.1[化学工程—有机化工]