盐酸洛美沙星缓释滴眼液的研制  

Studies and Preparation on Lomefloxacin Hydrochloride Sustained-release Eye Drops

作　　者：刘祖雄[1] 李晓东[1] 汤韧[1] 

机构地区：[1]广州军区武汉总医院药剂科,湖北武汉430070

出　　处：《中国药业》2002年第4期54-55,共2页China Pharmaceuticals

摘　　要：目的:研究盐酸洛美沙星缓释滴眼液的处方和制备工艺,建立制剂含量测定的方法,并对其稳定性进行初步探讨。方法:采用紫外分光光度法在287nm波长处测定盐酸洛美沙星缓释滴眼液中洛美沙星的含量,线性范围为1－7μg/mL。结果:平均回收率为99．97%,RSD为0．39%,结论:该制剂制备工艺简单,质量可控。ve: The prescription and preparation of Lomefloxacin hydrochloride sustained - release eye drops were designed and studies. The assay of content was set up and its stability was discussed primarily, methods: The content ofLomefolxacin was determined by spectrophotometry at wavelenth of 287nm, the linear range was 1-7μg/mL. results:The average recovery was 99.97% with RSD of 0.39%. conclusion: The preparation process of Lomefloxacin hy-drochloride sustained - release eye drops was simple. The quality could be controled.

关 键 词：盐酸洛美沙星 缓释滴眼液 制备 质量控制 

分 类 号：R978.19[医药卫生—药品] R944.1[医药卫生—药学]