组织干细胞的研究进展  

Progress on the Study of Tissue Stem Cells

作　　者：侯玲玲[1] 曹华[1] 张涌[2] 裴雪涛[1] 

机构地区：[1]军事医学科学院输血研究所,北京100850 [2]西北农林科技大学,杨凌712100

出　　处：《中国实验血液学杂志》2002年第2期159-162,共4页Journal of Experimental Hematology

摘　　要：干细胞是个体生命过程中产生和存在的具有高度自我更新能力和多向分化潜能的细胞群体。目前 ,在干细胞工程领域主要以胚胎干细胞和组织干细胞为研究对象 ,同时随着组织工程的发展 ,细胞的替代治疗已成为治疗一些疾病的新途径。组织干细胞在体外被扩增和定向诱导为一些所需细胞 ,然后植入患者体内 ,用以修复损伤 ,替代退行性组织 ,以及改善遗传性缺陷组织的功能。本文结合近几年国内外干细胞的研究进展 。Stem cells which exist in the individual life are the cell population with high self renewal capacity and multiple differentiation potential. At present, embryonic stem cells and tissue stem cells are the major objects for study in the field of stem cell engineering. At the same time, with the development of tissue engineering, cell replacement therapy became a new approach to treat some diseases. Tissue stem cells were tried to expand and committedly induce in vitro to some cells that are needed, then implanted them into patients to repair damage, replace regressive tissue and improve the function of hereditarily defect tissue. Based on recent progress of reseach on stem cells, this paper reviewed the biological characters and clinic application prospects of tissue stem cells.

关 键 词：组织干细胞 生物学特性 干细胞工程 临床应用 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]