过氧化氢直接氧化法合成2,3,5-三甲基氢醌  

Synthesis of 2,3,5 - Trimethylhydroquinone by Direct Oxidation Using Hydrogen Peroxide

作　　者：陈红[1] 吴缨[1] 徐国梅[1] 

机构地区：[1]合肥联合大学化学生物工程系,合肥230022

出　　处：《精细石油化工进展》2002年第4期25-27,共3页Advances in Fine Petrochemicals

摘　　要：以偏三甲苯为原料,H_2O_2-CH_3COOH-H_2SO_4为氧化体系,直接氧化合成2,3,5-三甲基氢醌(TMHQ)。通过正交试验,考察了影响氧化反应的各种因素,确定了氧化反应的最佳条件:反应温度70℃,H_2O_2与偏三甲苯(TMB)的摩尔比为6.5:1,H_2SO_4与TMB的摩尔比为3:1,反应时间3 h。在此条件下,产品纯度达92.13％。2,3,5 - Trimethylhydroquinone was synthesized from 1,2,4- trimethylbenzene (TMB) by direct oxidation using H2O2 - CH3COOH - H2SO4 as oxidation system. The effects of various factors on the oxidation were investigated by means of orthogonal test. The optimum conditions of the oxidation were determined as follows : reaction temperature 70 ℃, molar ratio of H2O2/TMB 6.5:1, molar ratio of H2SO4/TMB 3:1, reaction time 3 h. The purity of product was up to 92.13% .

关 键 词：偏三甲苯 过氧化氢 直接氧化法 合成 2 3 5-三甲基氢醌 

分 类 号：TQ24[化学工程—有机化工]