PAN-Co配合物用于维生素B_(12)的示波测定  

Oscillographic Determination of VB_(12) via PAN-Co Coordination Compound

作　　者：索志荣[1] 张宏芳[1] 于浩[1] 郑建斌[1] 

机构地区：[1]西北大学电分析化学研究所,西安710069

出　　处：《应用化学》2002年第4期381-383,共3页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金 (2 9775 0 18);国家教育部高等学校骨干教师资助计划项目 (GG-15 0 -710 0 6-2 877);陕西省教育厅自然科学专项基金 (0 1JK0 76)资助项目

摘　　要：Pyridylazo) 2 naphthol(PAN) can cause a sensitive incision on the oscillogram in NaOH solution, and the incision depth would decrease linearly with the increase of the concentration of Co 2+ . Based on this oscillographic characteristic, second order differential oscillographic voltammety is developed for Co 2+ determination. The linear range of the determination of Co 2+ is 2 00×10 -7 ～ 8 20×10 -6 mol/L and the detection limit is 1 00×10 -7 mol/L. RSD is 1 8% for eight successful determinations of 4 20×10 -6 mol/L Co 2+ . Satisfactory results were obtained by this method in determination of VB 12 content in VB 12 injection liquid.Pyridylazo) 2 naphthol(PAN) can cause a sensitive incision on the oscillogram in NaOH solution, and the incision depth would decrease linearly with the increase of the concentration of Co 2+ . Based on this oscillographic characteristic, second order differential oscillographic voltammety is developed for Co 2+ determination. The linear range of the determination of Co 2+ is 2 00×10 -7 ～ 8 20×10 -6 mol/L and the detection limit is 1 00×10 -7 mol/L. RSD is 1 8% for eight successful determinations of 4 20×10 -6 mol/L Co 2+ . Satisfactory results were obtained by this method in determination of VB 12 content in VB 12 injection liquid.

关 键 词：维生素B12 示波分析 简易示波伏安法 (吡啶偶氮)萘酚 钴配合物 药物含量测定 

分 类 号：R977.22[医药卫生—药品] R927.2[医药卫生—药学]