超声心动图对新生儿持续肺动脉高压的诊断及疗效评价  

Evaluating the Value of Echocardiography on Diagnosis and Therapeutic Observation of persistent Pulmonary Hypertension of neonate

作　　者：王芳韵[1] 金兰中[1] 马桂琴[1] 李国敏[1] 崔威[1] 

机构地区：[1]首都医科大学附属北京儿童医院功能检查科,北京市100045

出　　处：《中国超声医学杂志》2002年第5期373-375,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 :探讨超声心动图对新生儿持续肺动脉高压的诊断及临床疗效观察价值。方法 :经超声心动图证实存在肺动脉高压 ,除动脉导管和卵圆孔未闭外 ,不伴其它心脏结构异常的 2 6例新生儿的临床及超声心动图资料 ,并根据所测肺动脉收缩压值高低 ,将患儿分为轻、中、重三组。结果 :轻和中度组患儿各 9例 (各占 35 % ) ,肺动脉收缩压分别为 (41.5 1± 5 .0 1) mm Hg、 (5 4 .2 1± 3.0 0 ) mm Hg;重度组患儿 8例 (30 % ) ,肺动脉收缩压为 (90 .13±11.4 0 ) mm Hg。治疗 1周后复查 ,轻度组 9例 (10 0 % )、中度组 5例 (5 5 .6 % )、重度组 1例 (12 .5 % ) ,患儿肺动脉收缩压降至正常。 2周后中度组另 4例、重度组另 1例患儿肺动脉收缩压降至正常。超声心动图所测结果与患儿临床表现转归一致。结论 :超声心动图是新生儿持续肺动脉高压最重要的无创诊断方法之一 ,它不仅有助临床确诊 ,对临床判断病情轻重。Objective:To evaluate the value of echocardiography (ECHO) on the diagnosis and the therapeutic observation of persistent pulmonary hypertension of the neonate (PPHN).Methods:The clinical and ECHO data of 26 neonates with pulmonary hypertension identified by ECHO, and free of structural cardiac lesions except patent ductus arteriosus and patent foramen oval were studied and followed up.According to the measured pulmonary artery systolic pressure(PASP) value the patients were divided into mild,moderate group and severe group.Results:There were both 9 cases (35%)belong to mild and moderate group and 8 cases (30%) belong to severe group with PASP 41 51±5 01mmHg,54 21±3 00mmHg and 90 13±11 40mmHg respectively. One week after treatment the PASP of 9/9 cases in mild, 5/9 cases in moderate group and 1/8 case in severe group decreased to normal level. Two weeks later the data of the another 4/9 cases in moderate group and 1/9 case in severe group decreased to normal level. The results of ECHO were consistent with clinical symptoms. Conclusions:ECHO is one of the most important method on the diagnosis of PPHN, and it could not only helpful on ascertain diagnosis but also had important value on judgement of illness degree, observation of therapentic effects and forecasting prognosis for clinic.

关 键 词：超声心动图 新生儿 持续肺动脉高压 诊断 疗效评价 

分 类 号：R445.1[医药卫生—影像医学与核医学]