应用发光分析技术测定带Cu-IUD大白鼠子宫腔渗出细胞的吞噬活性  

Phagocytosis of Infiltrating Cells in Uterine Cavity of Cu-IUD-Wearing Rats by Chemiluminescence Technique

作　　者：刘永强[1] 吴熙瑞[1] 李荣[2] 

机构地区：[1]同济医科大学生殖医学中心 [2]同济医科大学基础医学部生物学教研室

出　　处：《同济医科大学学报》1991年第1期35-37,共3页Acta Universitatis Medicinae Tongji

摘　　要：本文应用化学发光技术测定了大白鼠带Cu-IUD后,在急性期、慢性期和着床期官腔内渗出细胞的吞噬活性。结果发现:急性期其吞噬活性很活跃,吞噬发光强度在15min时达到峰值(5.8±3.4cps);慢性期吞噬活性仍明显高于对照侧,发光强度持续增强,45min时达1.8±0.8cps;交配后吞噬活性进一步增强,发光强度45min时达4.2±3.1cps,提示带器后宫腔渗出细胞的吞噬活性与IUD的避孕机理有一定关系。In this study, chemiluminescence (CL) technique was developed to analyse the phagocytosis of infiltrating cells in uterine cavity of rats wearing Cu-IUD in the periods of acute, chronic inflammation and in the term of implantation. In acute period, phagocytosis of infiltrating cells was active, the peak of CL reaching 5.8±3.4cps at 15 min of incubation with opsonizd zymosan, while in chronic period, the phagocytosis was lower, CL being 1.8±0.6 cps at 45 min. However, phagocytosis of infiltrating cells was enhanced in the term of implantation, CL reaching 4.2±3.1 cps at 45 min. The above findings suggest that phagocytosis of infiltrating cells in IUD-wearing uterine cavity is related to the mechanism of contraception of IUD.

关 键 词：避孕 宫内节育器 铜 吞shi作用 

分 类 号：R169.41[医药卫生—公共卫生与预防医学]