一种用于识别肌酸酐分子的荧光化学敏感器  

A Fluorescent Chemosensor for Recognition of Creatinine

作　　者：梅明华[1] 吴世康[1] 

机构地区：[1]中国科学院理化技术研究所,北京100101

出　　处：《化学学报》2002年第5期866-869,共4页Acta Chimica Sinica

基　　金：国家科技部 973(No.G2 0 0 0 0 7810 0 )资助项目

摘　　要：合成了一种对肌酸酐分子有选择识别能力的敏感器 ,它可通过氢键相互作用而和肌酸酐分子相络合 ,并在络合的同时引起敏感器荧光强度的增大以达到识别的指示作用 .对几种可能产生干扰作用的化合物如脲素、氨基酸是否对该敏感器分子的工作有所干扰进行了试验 。A fluorescent sensor for selective recognition of creatinine was synthesized. The formation of its complex with creatinine through hydrogen bonding interaction resulted in the improvement of fluorescence intensity of the sensor. The disturbance of several compounds such as urea and amino acid to the creatinine recognition of the sensor was tested. The result indicates that the artificial sensor obtained has specificity for the creatinine recognition.

关 键 词：分子识别 肌酸酐 荧光化学敏感器 氢键相互作用 血液 临床检验 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]