黄杉化学成分的研究  

STUDIES ON THE CHEMICAL CONSTITUENTS OF PSEUDOTSUGA SINENSIS

作　　者：易进海[1] 张国林[2] 李伯刚[2] 

机构地区：[1]四川省中药研究所,四川成都610041 [2]中国科学院成都生物研究所,四川成都610041

出　　处：《药学学报》2002年第5期352-354,共3页Acta Pharmaceutica Sinica

摘　　要：目的　研究黄杉的化学成分。方法　用色谱方法分离黄杉化学成分 ,用波谱技术 (IR ,UV ,MS ,1D和 2D NMR)鉴定结构。结果　从黄杉树皮中分离得到 6个化合物 ,分别鉴定为 5 ,7,4′ trihydroxy 6 methylflavanone (poriol,I) ,3,5 ,7,3′ ,4′ pentahydroxyflavonone (quercetin ,II) ,5 ,7,3′,5′ tetrahydroxy 6 methylflavanone (III) ,5 ,7,3′ ,5′ tetrahydroxyflavanone (IV) ,3,5 ,7,3′ ,5′ pentahydroxyflavanone (V)和 5 hydroxy 6 methylchromone 7 O β D glucopyranoside(VI)。结论　III ,VI为新化合物 ,所得 6个化合物均为首次从该属植物中分得。AIM To study the chemical constituents of Pseudotsuga sinensis Dode (Pinaceae). METHODS To separate the constituents of P.sinensis by using various kinds of chr omatography and identify their structures on the basis of spectral analysis. RESULTS Six compounds were isolated from P. sinensis. Their structures were established as 5,7,4′ trihydroxy 6 methylflavanone (poriol, I), 3,5,7,3′,4′ pentahydroxyflavonone (querce tin, II), 5,7,3′,5′ tetrahydroxy 6 methylflavano ne (III), 5,7,3′,5′ tetrahydroxyflavanone (IV), 3,5,7,3′,5′ pentahydroxyflavanone (V) and 5 hydroxy 6 methylchromone 7 O β D glucopyranoside (VI) based on the analysis of spectral data of IR , UV, MS, 1D and 2D NMR. CONCLUSION Compounds III and VI are new compounds. All of six compounds were isolated from this plant for the first time.

关 键 词：黄杉 黄酮 植物药 中药 化学成分 

分 类 号：R282.71[医药卫生—中药学] R284[医药卫生—中医学]