噻氯匹啶格列齐特治疗糖尿病40例  

Gliclazide in Combination with Ticlopidine in the Treatment of 40 Cases of Diabetes Mellitus

作　　者：宋瑄[1] 林楠[2] 郭玉显[1] 

机构地区：[1]山东省青岛市人民医院内科,266001 [2]山东省青岛大学医学院附属医院急诊科,266003

出　　处：《医药导报》2002年第5期282-283,共2页Herald of Medicine

摘　　要：目的 :探讨噻氯匹啶对Ⅱ型糖尿病患者血糖、血脂、血液流变学的影响。方法 :治疗组 40例 ,同时口服格列齐特 80mg ,bid和噻氯匹啶 2 5 0mg ,qd。对照组 2 0例 ,口服格列齐特 80mg ,bid。疗程均为 2周。结果 :治疗组有效率87.5 % ,对照组有效率 6 5 .0 % (P <0 .0 5 ) ;治疗组血脂、血液流变学指标均有改善 ,与对照组比较 ,差异有极显著性 (P <0 .0 1)。结论 :噻氯匹啶可作为Ⅱ型糖尿病患者的辅助治疗药物。Objective:To study the effect of ticlopidine on blood glucose, lipid and blood rheology in patients with type Ⅱdiabetes mellitus. Methods:40 patients in the treatment group were given each 80 mg of gliclazide b.i.d. and 250 mg of ticlopidine q.d., while only 80 mg of gliclazide b.i.d were administerd to each of 20 cases in the control group. The course lasted 2 weeks in both groups. Results:The clinical cure rate were 87.5% and 65.0% in the treatment group and control group respectively. The situation of blood lipid profiles and blood rheology was much better improved in the treatment group than in the control group. The differences between these parameters of the two groups are highly significant (P<0.01). Conclusion:Ticlopidine can be used as an auxiliary medicine in the treatment of patients with type Ⅱ diabetes mellitus.

关 键 词：噻氯匹啶 格列齐特 糖尿病 Ⅱ型 

分 类 号：R977.15[医药卫生—药品]