甲磺酸培氟沙星霜的研制和稳定性观察  

Preparation of and Observation on the Stability of Pefloxacin Mesylate Cream

作　　者：刘祖雄[1] 李晓东[1] 王平[1] 汤韧[1] 

机构地区：[1]广州军区武汉总医院药剂科,武汉430070

出　　处：《医药导报》2002年第5期307-308,共2页Herald of Medicine

摘　　要：目的 :研究甲磺酸培氟沙星霜的制备、质量标准。方法 :采用紫外分光光度法测定含量 ,并考察其稳定性、刺激性。结果 :该制剂平均回收率 99.97% ,RSD 0 .16 %。结论 :该制剂制备工艺简单 ,使用方便 ,值得临床推广。Objective:To study the preparation and quality standard of pefloxacin mesylate cream. Method:The content of pefloxacin in the cream was determined with UV spectrophotometry, while its stability and irritating property were examined. Results:The average rate of recovery of the preparadfon was 99.7%, with an RSD of 0.16%. The preparation was stable its quality controllable. Conclusion: The technology of the preparation of the cream is simple and it is convenient to use the drug. We therefore suggest to spread its clinical application.

关 键 词：培氟沙星 甲磺酸 质量控制 稳定性 

分 类 号：R978.19[医药卫生—药品]