发育期长骨生长板的MRI与解剖组织学实验研究  

A Experimental Study of Growth-plate of Developmental Long Bones:MRI,Anatomy and Histology

作　　者：朱绍成[1] 史大鹏[1] 周存升[2] 孔令非[3] 连建敏[1] 

机构地区：[1]河南省人民医院放射科,河南郑州450003 [2]山东省医学影像学研究所 [3]河南省人民医院病理科

出　　处：《实用放射学杂志》2002年第4期261-264,共4页Journal of Practical Radiology

基　　金：河南省科技攻关项目 (编号 0 1 2 4 1 70 1 0 7)

摘　　要：目的　探讨长骨生长板的MRI表现及其与解剖组织学的关系。方法　使用 1.0TMR扫描仪对 40例健康纯种长白猪行膝关节冠状位及矢状位不同序列扫描 ;并将生长板MRI表现与其断面解剖及组织学相对照。结果　根据 40例实验动物膝关节生长板MRI表现 ,可将生长板的发育分为四个阶段 :即生长板形成前期、生长板形成期、生长板平衡期和生长板闭合期 ,分别相当于妊娠 80～ 95d、妊娠 95d～出生后 2个月、2个月～ 3.5年和 3.5～ 4.5年。不同时期膝关节生长板MRI表现可真实反映标本的断面解剖结构 ,并可在一定程度上反映其组织学表现。结论　MRI检查可准确用于生长板发育过程的分期、正常解剖及组织学基础的推测 ,有利于生长板病变的诊断与鉴别诊断。Objective To describe the MR appearancses of growth-plate of the developmental long bones,and to study the correlativity of MRI with the anatomy and histology findings.Methods 40 pigs with normal knees were examined by 1.0 T scanning system with various orientations and sequences,MR imagings were compared with the results of sectional anatomy and histology.Results According to MRI,we divided the evolution of growth plate into four developmental stages;the earlier forming stage of growth plate(aged the 80～95 days of pregnancy),the forming stage(aged the 95 days of pregnancy-2 months),the maintaining stage (aged 2 months-3.5 years),the closing stage(aged 3.5～4.5 years).The MRI manifestations of growth plate of knees reflected the findings of sectional anatomy perfectly and histology to a certain extent in each developmental stage.Conclusion MRI is very useful and helpful in dividing the developmental stages of growth-plate,guessing the foundation of anatomy and histology,diagnosing and differentiating all kinds of growth plate lesions.

关 键 词：发育期 长骨生长板 MRI 解剖组织学 实验研究 长骨发育 

分 类 号：R336[医药卫生—人体生理学] R445.2[医药卫生—基础医学]