糖尿病肾病患者凝血、纤溶状态的研究  

A study on the coagulation and fibrinolysis state of patients with diabetic nephropathy

作　　者：孙雪峰[1] 周希静[2] 严海东[2] 李曼[2] 王力宁[2] 

机构地区：[1]中山医科大学附属第一医院肾科,广州510080 [2]中国医科大学附属第一医院肾内科,沈阳110001

出　　处：《中国实用内科杂志》2002年第5期273-274,共2页Chinese Journal of Practical Internal Medicine

摘　　要：目的　探讨糖尿病肾病患者的凝血、纤溶状态。方法　 2型糖尿病、糖尿病肾病 (DN)患者 2 7例 (DN组 ) ;慢性肾小球肾炎患者 2 3例 (CGN组 )。酶联免疫吸附法系统检测各项凝血、纤溶指标。结果　与CGN组患者相比 ,DN组患者的各项凝血、纤溶指标明显增高。结论　DN患者存在有较慢性肾小球肾炎患者更强的凝血、纤溶活性 ,亦存在相对凝血亢进的纤溶活性不足。Objectives To investigate the states of coagulation and fibrinolysis in diabetes nephropathy.Methods Parameters of coagulation-fibrinolysis were measured by ELISA in 27 type Ⅱ, diabetic nephropathy (DN group) and 23 chronic glomerulonephritis patients (CGN group). Results The parameters of coagulation -fibrinolysis levels in DN group were significantly higher than those in CGN group.Conclusions The activity of coagulation -fibrinolysis in DN patients was more than those of chronic glomerulonephritis patients, but the activity of fibrinolysis showed relatively insufficient compared to increased activity of coagulation.

关 键 词：糖尿病肾病 凝血 纤溶 研究 慢性肾小球肾炎 

分 类 号：R587.2[医药卫生—内分泌] R692[医药卫生—内科学]