山莨菪碱联用地塞米松治疗恙虫病并多脏器损害的研究——附70例报告  

A Study on Anisodomine Combining with Dexamethasone Treatments in Patients with Tustusgamushi Disease Complicated by Multiple Organ Dysfunction——70 cases reports

作　　者：黄昭穗[1] 欧阳万青[1] 刘开渊[1] 黄胜立[1] 陈志忠[1] 

机构地区：[1]中国人民解放军第九五医院内科,351100

出　　处：《福建医药杂志》2002年第2期4-5,共2页Fujian Medical Journal

摘　　要：目的　探讨山莨菪碱联用地塞米松治疗恙虫病并多脏器系统损害的疗效。方法　治疗组 :氯霉素 1 .5g加5%葡萄糖液 50 0 ml静滴 ,每日 1次 ,连用 7天 ;山莨菪碱 1 0 mg、地塞米松 1 0 mg加 5%葡萄糖液 50 0 ml静滴 ,每日 1次 ,连用 3天 ;对照组单用氯霉素治疗。结果　治疗组体温恢复正常 ,各系统症状消失 ,多脏器功能恢复正常时间均较对照组短 ,平均住院时间缩短 4天 ,死亡率下降 2 .85%。结论　恙虫病合并多脏器系统损害除了积极选用氯霉素治疗外 ,联合短程应用山莨菪碱及地塞米松可以有效改善器官功能 。Objective To investigate the effect of anisodomine combining with dexamethasone treatments in patients with tustusgamushi disease complicated by MOD.Methods The treatment group received chloramphenicol 1 5g daily with a course of 7 days,anisodomine 10mg daily and dexamethasone 10mg daily with a course of 3 days.The group of controls was produced only with chloramphenicol.Results In the treatment group,the clinical course of temperature and complaints and organization harm restore was decreased,and the average course in hospital was decreased by four days,mortality rate was decreased by 2 85per cent.Conclusion The study shows that anisodomine combining with dexamethasone can increase organs function and decrease mortality rate in patients with tustusgamushi disease complicated by MOD.

关 键 词：山莨菪碱 地塞米松 恙虫病 多脏器损害 并发症 联合治疗 研究 

分 类 号：R513.2[医药卫生—内科学] R59[医药卫生—临床医学]