火鸡出血性肠炎病毒分子生物学研究进展  

The Molecular Biology Progress of Hemorrhagic Enteritis Virus in Turkey

作　　者：邹云莲[1] 俞乃胜[1] 

机构地区：[1]云南农业大学动物科学技术学院,云南昆明650201

出　　处：《动物医学进展》2002年第3期5-8,共4页Progress In Veterinary Medicine

摘　　要：本文阐述了火鸡出血性肠炎病毒近年来在分子生物学方面的研究进展。HEV基因组全长 2 62 63 bp,是目前所知道最短的禽腺病毒。基因组中 G+C含量为 3 4.93 %。与其它腺病毒相似 ,含有 3 9bp的末端重复序列。晚期蛋白基因 ( 52 k, a,五邻体 ,核心蛋白 ,六邻体 ,肽链内切酶 ,1 0 0 k,P ,和纤维蛋白 ) ,早期基因(聚合病毒 ,末端蛋白 ,DNA结合蛋白 )和中期基因 VIa2及其编码蛋白与其它腺病毒相比具有相似性。基因组中无明显的 E1、E4区。然而 ,作为腺病毒分类的三个标准即基因组长度、末端重复序列及 G+C含量 ,其与牛腺病毒在分类地位上最接近。This paper introduces the molecular progress of Hemorrhagic enteritis virus(HEV) in turkey. The full length of genome is 26 263 bp, shorter than any Ads found so far. The G+C content is 34.93%. There are 39bp terminal repeat and similar to other Ads. The late gene(52k,Ⅲa, penton base, core protein, hexon, endopeptidase, 100k, p Ⅷ , and fiber), early region 2 genes (polymerase, terminal protein, and DNA binding protein), intermediate genes and their coding proteins are stated. No sequences similar to E1 and E4 region were found. However, compared HEV with other Ads through the full length of genome, the terminal repeat and the G+C content, we find that the statue of HEV is close to ovine adenovirus rather than avian adenovirus. Open reading frames are identified with no similarity to any published Ad sequence.

关 键 词：火鸡 出血性肠炎病毒 分子生物学 研究进展 

分 类 号：S858.395.3[农业科学—临床兽医学] S852.65[农业科学—兽医学]