碳十八键合锆胶固定相的制备与色谱性能评价  

Preparation and Evaluation of Octadecyl-Zirconia Bonded Stationary Phases

作　　者：扬俊佼 王晖[1] 左育民[1] 

机构地区：[1]南开大学化学系,天津300071

出　　处：《高等学校化学学报》2002年第5期835-838,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:2957201)资助.

摘　　要：用诱导聚合胶体凝聚法（PICA）制得的二氧化锆微球与碳十八三乙氧基硅烷反应制备了碳十八键合锆胶基质固定相（ODZ）．评价了该柱填料的色谱性能，并用此固定相分离了中性和碱性化合物．Abstract Porous zirconia particles, synthesized by polymerization-induced colloid aggregation (PICA)method, were modified with octadecyltrimethoxysilane compounds for reversed-phase high-performanceliquid chromatography. These stationary phases were evaluated in terms of reversed-phase chro-matographic properties with different volume ratos of methanol to water. Stability studies conducted at anextreme pH (pH = 2. 0 and pH = 12. 0) have shown that octadecyl-zirconia sorbents are no more stablethan ODS under acidic conditions, but rather stable under basic conditions. The retention of non-polar andslightly polar compounds was quasi-homoenergetic on octadecyl-zirconia stationary phases.

关 键 词：碳十八键合锆胶固定相 制备 色谱性能 评价 二氧化锆 诱导聚合胶体凝聚法 高效液相色谱 

分 类 号：O657.72[理学—分析化学]