不孕妇女宫颈沙眼衣原体感染的临床观察  

Clinical Observation of Chlamydia Trachomatis Infection in Cervical Mucus on Sterility Women

作　　者：郝翠芳[1] 曹积功[1] 杨秋花[1] 侯南英[1] 刘秀丽[1] 李宁[1] 张宁[1] 王文娟[1] 

机构地区：[1]青岛大学医学院附属烟台毓璜顶医院,山东烟台264000

出　　处：《实用妇产科杂志》2002年第3期183-184,共2页Journal of Practical Obstetrics and Gynecology

摘　　要：目的 :探讨宫颈沙眼衣原体 (CT)感染对生育的影响。方法 :应用聚合酶链反应 (PCR)技术 ,对 2 16对不孕夫妇宫颈分泌物、尿道分泌物进行 CT- DNA检测 ,并观察宫颈 CT感染对围排卵期宫颈粘液葡萄糖含量及性交后试验的影响。结果 :2 16对不孕夫妇衣原体感染的阳性率分别为 :女性 32 .4 % ,男性 30 .1%。宫颈 CT感染妇女围排卵期性交后试验与未感染妇女比较 ,每高倍视野的活精数明显减少 (P<0 .0 5 ) ,围排卵期宫颈粘液葡萄糖含量明显减少 (P<0 .0 1)。经治疗后宫颈 CT转阴的妇女 ,围排卵期性交后试验每高倍视野的活精数明显高于治疗前 (P<0 .0 5 ) ,宫颈粘液的葡萄糖含量亦明显高于治疗前 (P<0 .0 1)。治疗后宫颈 CT持续阳性妇女 ,围排卵期性交后试验与治疗前比较 ,每高倍视野的活精数无明显变化 (P>0 .0 5 ) ,宫颈粘液的葡萄糖含量亦无明显变化 (P>0 .0 5 )。结论 :宫颈 CT- DNA感染是不孕的一个重要因素 ,导致不孕的原因 ,可能与患者宫颈粘液葡萄糖含量降低 。Objectives:To discuss the effect of chlamydia trachomatis(CT)infection on sterility.Methods: The polymerase chain reaction (PCR) technique was used to detect CT DNA in samples from the cervical canal and male urethra of 216 sterility couples.At meantime sexual intercourse test was observed and the glucose levels of cervical mucous was determined.Results: The positive rates of CT-DNA in 216 sterility couples were 32.4%(female) and 30.1%(male) respectively.Sexual intercourse test and glucose levels results was showed:activity sperms of per high power field were significantly lower( P <0.05)and glucose levels of cervical mucous was reduced ( P <0.01) in CT DNA positive patients than CT DNA negative patients; After treatment of positive patients,activity sperms of per high power field were significantly higher ( P <0.05) and glucose levels of cervical mucous was significantly increase ( P <0.01) in those patients became negative than those patients before treatment;activity sperms of per high power field were no significant differences( P >0.05) and glucose levels of cervical mucous were no differences ( P >0.05) in those patients remained positive before and after treatment.Conclusion: there is a strong association between sperm activities,glucose levels of cervical mucous and cervical canal infection with CT-DNA.

关 键 词：不孕 妇女 宫颈 沙眼衣原体感染 临床观察 聚合酶链反应 性交后试验 

分 类 号：R711.6[医药卫生—妇产科学]