睡眠呼吸暂停综合征患者夜间低氧血症与高血压的关系  

Relationship between Hypoxemia at Night Caused by Sleep Apnoea Syndrome and Hypertension

作　　者：林红英[1] 丁树枝[1] 王志良[1] 刘昌起[1] 

机构地区：[1]天津市胸科医院胸内科,300051

出　　处：《天津医药》2002年第5期265-266,共2页Tianjin Medical Journal

摘　　要：目的:探讨睡眠呼吸暂停综合证(SAS)患者夜间低氧血症与高血压是否有关　 方法:对102例SAS患者以睡眠呼吸紊乱指数(AHI)将SAS分为轻度、中度和重度3组,将每组再分为高血压和非高血压两组. 统计各组高血压睡前、睡后和总高血压的发生率,进行高血压和非高血压组氧合状态的各项参数比较。结果:随着SAS的加重,高血压的发生率增加,3组分别为39％、45％和54％,总发生率为49％ 尤其是睡后高血压中度和重度SAS组均较轻度组增加。其次,不同程度SAS组高血压与非高血压之间夜间血氧饱和度(SaO2)和氧减饱和度指数(ODI)均无统计学差异。结论:SAS病人49％有不同程度的高血压,而且随着SAS程度的加重,并发高血压者也增加,尤其是睡后和睡前、睡后均高的高血压合并发生率增加,因此SAS应用为高血压的独立危险因素。Objective: To study the relationship between hypoxemia at night caused by sleep apnoea syndrome (SAS) and hypertension. Methods: According to AHI, 102 patients with SAS were divided into mild, moderate and serious SAS groups. Each group was divided into hypertension and non-hypertension subgroups. The blood pressure before and after sleep and the incidence of hypertension of each group were recorded. Various oxygenation parameters were compared between the subgroups. Results: The overall incidence of hypertension was 49% , the incidences in the mild, moderate and serious SAS groups were 39% , 45% and 54% respectively. In addition, there was no difference of SaO; and GDI between the subgroups. Conclusion: The incidence of hypertension increases along with the worsening of SAS degree, so SAS should be regarded as an independent risk factor of hypertension.

关 键 词：睡眠呼吸暂停综合征 夜间 低氧血症 高血压 

分 类 号：R766.43[医药卫生—耳鼻咽喉科] R544.1[医药卫生—临床医学]