高血压患者脉压差与颈动脉粥样硬化的关系  

Relationship between Ambulatory Pulse Pressure and Carotid Artery Atherosclerosis in Patients with Essential Hypertension

作　　者：张广明[1] 孙雯[1] 冯淑芝[1] 曹丽[1] 罗洁[1] 张佚[1] 王佩显[1] 任晓阳[2] 

机构地区：[1]天津医科大学总医院老年病研究室,300052 [2]天津医院

出　　处：《天津医药》2002年第5期289-290,共2页Tianjin Medical Journal

摘　　要：目的:探讨高血压(EH)患者脉压差(PP)与颈动脉内膜-中层厚度(IMT)、颈动脉横截面积(CSA)的关系。方法:在接受24h动态血压监测(ABPM)的EH患者中,按PP 75 mmHg为界分为两组,每组30例,应用多普勒超声检测IMT和CSA。结果:PP≥75mmHg组PP与IMT、CSA具有相关性,r分别为0.352,0.439(P<0.01)。PP≥75mmHg组IMT、CSA与PP<75mmHg组比较有显著性差异(P<0.01)。结论:EH患者PP增宽是IMT、CSA的重要血流动力学因素,可能是EH并发症的最佳预测因子。Objective: To determine the relationship between ambulatory pulse pressure (PP) and carotid artery atherosclerosis in patients with essential hypertension (EH). Methods: Patients with EH who had been subjected to 24 hours ambulatory blood pressure monitoring (ABPM) were divided into two groups on the basis of the PP 75 mmHg. Carotid intima-media thickness (IMT) and carotid artery cross-sectional area (CSA) were measured by color Doppler echocardiography. Results:In PP≥75 mmHg group, the mean value of PP had a positive correlation with IMT (r = 0.352) and CSA (0.439) (P <0.01). There was a significant difference between PP≥75 and <75 mmHg groups (P<0.01). Conclusion: A widenedPP is an important risk predictor for the severity of carotid artery lesions and complications of EH.

关 键 词：高血压 脉压差 颈动脉粥样硬化 血压测定 

分 类 号：R544.1[医药卫生—心血管疾病] R543.4[医药卫生—内科学]