工作场所空气中三氯硫磷卫生标准的研究  

Study on the Health Standard for Thiophosphoryl Chloride in the Air of Workplace

作　　者：杨校华[1] 沈芸芝[1] 马藻骅[2] 乐俊仪[1] 孙建析[1] 邱木清 

机构地区：[1]浙江省医学科学院,浙江杭州310013 [2]宁波市卫生防疫站,宁波315010 [3]宁波农药厂环保处,宁波310000

出　　处：《环境与职业医学》2002年第2期90-92,共3页Journal of Environmental and Occupational Medicine

基　　金：卫生部卫生标准"九五"规划项目

摘　　要：[目的 ]研究工作场所空气中三氯硫磷卫生标准。 [方法 ]测定三氯硫磷的急性和亚急性毒性 ,并进行现场接触工人的职业流行病学调查。 [结果 ]三氯硫磷的大鼠经口LD50 为 681mg/kg ,慢性吸入阈浓度 2 0 6mg/m3 ,刺激阈浓度 8 5mg/m3 (大鼠 )。工作场所空气中三氯硫磷浓度 0 5mg/m3 以下 ,未发现接触工人中毒症状。 [结论 ]建议工作场所空气中三氯硫磷最高容许浓度为 0 5mg/m3 。To establish national health standard for thiophosphoryl chloride in the air of workplace. Occupational epidemiological investigation and studies on the acute toxicity and subchronic oral toxicity of thiophosphoryl chloride were conducted. The available literatures concerning standard setting were collected. LD 50 for thiophosphoryl chloride by intragastric administration is 660 mg/kg in rats. The threshold of chronic inhalation toxic effect in rats is 2 06 mg/m 3. The results of environmental monitoring showed that the most concentrations of thiophosphoryl chloride in the air of workplace were below 0 5 mg/m 3,the adverse effects related to exposure to thiophosphoryl chloride in workers were not found. [Conclusion] The maximum allowable concentration(MAC) for thiophosphoryl chloride in the air of workplace is recommeded as 0 5 mg/m 3.

关 键 词：工作场所 空气 卫生标准 研究 三氯硫磷 毒理学 最高容许浓度 现场调查 

分 类 号：R134.4[医药卫生—劳动卫生]